Genomics

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Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Despite the astounding advances made in understanding the biologic underpinnings of cancer, many cancers are missing obvious genetic drivers.

5 May 2023

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life.

5 May 2023

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Mini Organs Provide New Insights Into Fibrolamellar Carcinoma

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

4 May 2023

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

Researchers at the Department of Biology, University of Copenhagen, have now contributed to solving this problem for a specific gene called GCK. The study has just been published in Genome Biology.

4 May 2023

Study Advances Understanding of the Deep Evolutionary History of Viruses

Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.

3 May 2023

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.

3 May 2023

New Extraction Protocol Offers a More Comprehensive Picture of Cellular Activity

Researchers at the Van Andel Institute have created a new extraction protocol for RNA-seq and metabolomic analysis that provides a more comprehensive picture of cellular activity than either technique alone.

3 May 2023

Texas A&M Research Provides a Definitive Answer to the Evolutionary Timeline of Mammals

Research led by a team of scientists from the Texas A&M School of Veterinary Medicine and Biomedical Sciences puts to bed the heated scientific debate regarding the history of mammal diversification as it relates to the extinction of the non-avian dinosaurs.

2 May 2023

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

2 May 2023

New Approach Could Power the Development of Advanced Cell Therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

2 May 2023

Study Uncovers Somatic Mutations That Play a Role in Common Form of Adult Epilepsy

Epilepsy affects approximately 1-in-26 people and the most common form, known as temporal lobe epilepsy (TLE), often cannot be adequately treated with anti-seizure medications.

2 May 2023

Genome Sequencing of 'Lablab Bean' Paves Way for Wider Cultivation of the African Crop

An international team of researchers has fully sequenced the genome of a climate-resilient bean that could bolster food security in drought-prone regions.

2 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

Deletion of Human Genome Information Helped in Differentiation Between Humans and Other Mammals

As per new research headed by scientists at Yale and the Broad Institute of MIT and Harvard, what the human genome is missing when compared to the genomes of other primates may be as significant to the development of humankind as what has been added at the time of human evolutionary history.

28 Apr 2023

Csx28 Membrane Protein Enhances CRISPR's Anti-Viral Defense

CRISPR achieved scientific popularity for its capacity to quickly and precisely edit genes. At the core, however, CRISPR systems are immune systems that aid bacteria to safeguard themselves from viruses through targeting and abolishing viral RNA and DNA.

28 Apr 2023

Reprogramming the Aging Process to Effectively Promote Longevity

Human lifespan is associated with the aging of individual cells. Three years ago, a group of researchers from the University of California, San Diego, uncovered fundamental mechanisms underlying the aging process.

28 Apr 2023

The Origins of Human Accelerated Regions

Large parts of the human genome were changed over a million years ago due to a random event during egg or sperm formation that resulted in the deletion, duplication, or reversal of sections of DNA. Investigators have demonstrated that those structural variants likely set off a cascade of other fast alterations in human DNA that may underpin unique human traits, particularly the brain.

28 Apr 2023

Clouds Capable of Disseminatimg Antibiotic-Resistance Genes

The atmosphere is a huge dissemination route for bacteria bearing antibiotic-resistance genes. Clouds can transport these genes, according to a team of researchers from Université Laval and Université Clermont Auvergne.

28 Apr 2023

3D Genome Mapping may Lead to Targeted Therapeutic Options for Ependymoma

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

28 Apr 2023

Genomics

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

Mini Organs Provide New Insights Into Fibrolamellar Carcinoma

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

Study Advances Understanding of the Deep Evolutionary History of Viruses

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

New Extraction Protocol Offers a More Comprehensive Picture of Cellular Activity

Texas A&M Research Provides a Definitive Answer to the Evolutionary Timeline of Mammals

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

New Approach Could Power the Development of Advanced Cell Therapies

Study Uncovers Somatic Mutations That Play a Role in Common Form of Adult Epilepsy

Genome Sequencing of 'Lablab Bean' Paves Way for Wider Cultivation of the African Crop

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Deletion of Human Genome Information Helped in Differentiation Between Humans and Other Mammals

Csx28 Membrane Protein Enhances CRISPR's Anti-Viral Defense

Reprogramming the Aging Process to Effectively Promote Longevity

The Origins of Human Accelerated Regions

Clouds Capable of Disseminatimg Antibiotic-Resistance Genes

3D Genome Mapping may Lead to Targeted Therapeutic Options for Ependymoma

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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