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Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

Researchers discover a crucial and exploitable vulnerability in diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

4 Jan 2022

Scientists discover hotspots in the 'dark genome' associated with schizophrenia and bipolar disorder

Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.

24 Dec 2021

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

24 Dec 2021

People with inflammatory bowel disease have more fecal microplastics

Microplastics -; tiny pieces of plastic less than 5 mm in length –– are everywhere, from bottled water to food to air. According to recent estimates, people consume tens of thousands of these particles each year, with unknown health consequences.

23 Dec 2021

Ziath supports mental health charity for young people

Ziath Ltd are putting a bit of Christmas cheer in the hearts and minds of young people in London suffering from mental health issues.

From Ziath Ltd 21 Dec 2021

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Multiple changes in brain cells during the first month of embryonic development may contribute to schizophrenia later in life, according to a new study by Weill Cornell Medicine investigators.

17 Dec 2021

Gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National Institute on Aging and colleagues.

17 Dec 2021

Study targets metabolic pathways to identify sensitivities among cancer cells

Metabolic reprogramming, accepted as a hallmark of cancer, might indicate a vulnerability to be used by targeted cancer therapy.

17 Dec 2021

Study employs gene reactivation to treat Fragile X syndrome

Fragile X syndrome, or FXS—a principal genetic cause of autism—impacts around one in 6,000 females and one in 4,000 males.

17 Dec 2021

Adults with rare genetic changes have poorer health, says study

According to a study, grown-ups with certain genetic causes of mental health and other brain disorders had substantially increased rates of chronic disease.

17 Dec 2021

Protein protects against heart damage following cancer treatment

Cancer treatment is hard on the body, however for the patient to endure cancer, it is mostly necessary to undergo the treatment.

17 Dec 2021

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death.

From Institut Pasteur 15 Dec 2021

Driving up the immune response at tumor site may help boost immunotherapy

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

15 Dec 2021

Detecting high-impact rare genetic variants in individuals with severe schizophrenia

New research published in the Proceedings of the National Academy of Sciences shows that examining genetic mutations in individuals with severe schizophrenia can improve the ability to detect disease-associated rare genetic variants.

15 Dec 2021

Study provides new insight into the genetics of severe schizophrenia

Columbia University researchers have determined that individuals who suffer from the most severe form of schizophrenia have a significantly higher number of rare mutations than more typical forms of the illness.

14 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

13 Dec 2021

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Medical Condition News

Olfactory receptor gene may drive breast cancer metastasis to the brain

Researchers discover a crucial and exploitable vulnerability in diffuse large B cell lymphomas

Scientists discover hotspots in the 'dark genome' associated with schizophrenia and bipolar disorder

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

People with inflammatory bowel disease have more fecal microplastics

Ziath supports mental health charity for young people

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia

Study targets metabolic pathways to identify sensitivities among cancer cells

Study employs gene reactivation to treat Fragile X syndrome

Adults with rare genetic changes have poorer health, says study

Protein protects against heart damage following cancer treatment

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

Driving up the immune response at tumor site may help boost immunotherapy

Detecting high-impact rare genetic variants in individuals with severe schizophrenia

Study provides new insight into the genetics of severe schizophrenia

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

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