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Light-Activated Macrophages Show Increased Appetite for Cancer Cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

13 Aug 2024

Peers' Genetic Traits Impact Long-Term Risk for Substance Use and Psychiatric Disorders

Mom always said, "Choose your friends wisely." Now a study led by a Rutgers Health professor shows she was onto something: Their traits can rub off on you – especially ones that are in their genes.

12 Aug 2024

Exploring Retrotransposon-Derived DNA Zip Codes in Myeloma Cell Internalization

A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, "Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization."

12 Aug 2024

Emerging Treatments and Drug Repositioning for NAFLD and NASH

The current research on drug candidates and molecular targets being clinically tested for the treatment of non-alcoholic steatohepatitis (NASH) and NAFLD.

9 Aug 2024

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

The ability to alter or prevent the expression of faulty genes in the brain could be leveraged as a powerful therapeutic against neurodegenerative disease. However, the molecular underpinnings of the living brain are still largely inaccessible, hampering progress on such promising therapeutics.

9 Aug 2024

Single-Cell Analysis Uncovers Impact of TREM2 Mutation on Beta-Amyloid Plaques

Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset Alzheimer's disease.

8 Aug 2024

Breakthrough Compound ZTA-261 Shows Promise for Safer Lipid Disorder Treatment

Scientists at Nagoya University in Japan have made a significant breakthrough in treating lipid disorders.

8 Aug 2024

Study Explores the Role of Sex-Biased Gene Expression in Autism Risk During Prenatal Development

The cortex of prenatal donors to determine differentially expressed genes based on sex and potentially identify molecular and cellular mechanisms that contribute to ASD.

7 Aug 2024

Lipid Nanoparticle-Encapsulated miR-193a-3p Mimic INT-1B3 Boosts Anti-Tumor Immunity

A new research paper was published in Oncotarget's Volume 15 on July 12, 2024, entitled, "INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death."

6 Aug 2024

Unveiling the Roots of Deadly Infant Leukemia

Researchers at the Josep Carreras Leukaemia Research Institute have identified the genetic foundation for newborn B-cell Acute Lymphoblastic Leukaemia (B-ALL) glucocorticoid resistance through MLL gene rearrangements.

6 Aug 2024

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

2 Aug 2024

Discovery of Immune Cell Reservoirs Near Glioblastomas Offers New Treatment Possibilities

Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years.

1 Aug 2024

Gut Microbiome Influences Cancer Risk Through Carcinogen Metabolism

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world.

1 Aug 2024

Breakthrough Study Reveals Role of Tissue-Resident Memory T Cells in Lung Cancer Prognosis

An extensive analytical study performed at the Terasaki Institute and published in Frontiers in Immunology highlights the crucial role of tissue-resident memory T cells and how they influence the immune environment of patients with non-small cell lung cancer and their overall prognosis.

1 Aug 2024

Study Challenges Current Understanding of Parkinson's and Lewy Body Disease Onset

Early detection of Alzheimer's disease-related changes in Parkinson's disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-β (Aβ) and phosphorylated tau (p-tau) proteins.

1 Aug 2024

CRISPR-Cas Vs. Anti-CRISPR Proteins: The Battle Over Antibiotic Resistance In Bacteria

The relationship between antibiotic resistance in bacteria and the interactions between the CRISPR-Cas system and anti-CRISPR proteins.

30 Jul 2024

Innovative Model Creates Personalized Parkinson's Disease Brain Cells for Drug Testing

A new model developed by Brigham researchers rapidly converts stem cells to brain cells characteristic of Parkinson’s disease to create personalized stem cell models with opportunities to test treatments

29 Jul 2024

Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

The niche areas in which phenotypic screening continues to be advantageous over the targeted approach, and the recent advances in phenotypic screening technology that have increased their efficiency.

26 Jul 2024

Study Reveals Titin Mutation Effects on Cardiac Development and Atrial Fibrillation

Millions of adults have atrial fibrillation -; an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

25 Jul 2024

Oligodendrocytes as Producers of Amyloid Beta in Alzheimer's Disease

Oligodendrocytes are an important source of amyloid beta (Aβ) and play a key role in promoting neuronal dysfunction in Alzheimer's disease (AD), according to a study published July 23, 2024 in the open-access journal PLOS Biology by Rikesh Rajani and Marc Aurel Busche from the UK Dementia Research Institute at University College London, and colleagues.

24 Jul 2024

Medical Condition News

Light-Activated Macrophages Show Increased Appetite for Cancer Cells

Peers' Genetic Traits Impact Long-Term Risk for Substance Use and Psychiatric Disorders

Exploring Retrotransposon-Derived DNA Zip Codes in Myeloma Cell Internalization

Emerging Treatments and Drug Repositioning for NAFLD and NASH

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

Single-Cell Analysis Uncovers Impact of TREM2 Mutation on Beta-Amyloid Plaques

Breakthrough Compound ZTA-261 Shows Promise for Safer Lipid Disorder Treatment

Study Explores the Role of Sex-Biased Gene Expression in Autism Risk During Prenatal Development

Lipid Nanoparticle-Encapsulated miR-193a-3p Mimic INT-1B3 Boosts Anti-Tumor Immunity

Unveiling the Roots of Deadly Infant Leukemia

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Discovery of Immune Cell Reservoirs Near Glioblastomas Offers New Treatment Possibilities

Gut Microbiome Influences Cancer Risk Through Carcinogen Metabolism

Breakthrough Study Reveals Role of Tissue-Resident Memory T Cells in Lung Cancer Prognosis

Study Challenges Current Understanding of Parkinson's and Lewy Body Disease Onset

CRISPR-Cas Vs. Anti-CRISPR Proteins: The Battle Over Antibiotic Resistance In Bacteria

Innovative Model Creates Personalized Parkinson's Disease Brain Cells for Drug Testing

Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

Study Reveals Titin Mutation Effects on Cardiac Development and Atrial Fibrillation

Oligodendrocytes as Producers of Amyloid Beta in Alzheimer's Disease

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

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