Molecular & Structural Biology

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Study reveals mechanism by which propionic acid induces brain disorders

Korea Brain Research Institute (KBRI, headed by Suh Pann-ghill) announced on the 11th that the research team led by Dr. Mun Ji-young revealed the mechanism of autism induced by an imbalance of human gut microorganisms.

19 Jun 2020

Researchers sequence the genome of medicinal leeches

The results of new research published this week in Scientific Reports reveal insights that may have profound effects on the use of medicinal leeches in hospital-based medicine.

18 Jun 2020

New microscope looks at the different parameters that change during wound healing

Researchers at the GSK Center for Optical Molecular Imaging have developed a new microscope that looks at the different parameters that change during wound healing. They hope to use this technique to understand how skin disorders, such as foot ulcers in diabetic patients and psoriasis, can be treated.

18 Jun 2020

Fighting fish synchronize their attacks and also gene expression in the brain cells

When two betta fish are fighting for dominance, not only do their attacks mirror each other, but the gene expression in their brain cells also starts to align.

18 Jun 2020

cryo-EM images reveal proteins involved in brain activity

When the body continues to perform its daily biological processes neurotransmitters, regulate the level of electrical activity inside the brain.

18 Jun 2020

Researchers use lead sequencing to determine the structure of RNAs

Scientists from RUB and the University of Münster have created a technique to simultaneously establish the structures of all RNA molecules in a bacterial cell.

18 Jun 2020

Structural map reveals changes in SMCHD1 protein linked to degenerative conditions

Researchers have used structural biology to map a portion of a protein called SMCHD1, describing how certain modifications can lead to degenerative conditions.

18 Jun 2020

NJIT researchers develop new efficient method to quantify therapeutic proteins

Researchers at New Jersey Institute of Technology in collaboration with Ohio University and Merck & Co. Inc. recently developed a new efficient method for targeted protein analysis -- one they say could speed up processes for disease testing, drug discovery and vaccine development.

18 Jun 2020

New system of gene editing allows for targeted, super-fast DNA repair

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

EEG study in split-brain patients shines light on sleep slow waves

The particular kind of waves that the brain produces during sleep, which repeatedly sweep the surface of the cerebral cortex, travel through the anatomical "highways" that connect distant areas of the cortical mantle, a new study in The Journal of Neuroscience shows.

18 Jun 2020

Dysfunctional placenta can contribute to Cornelia de Lange syndrome

Researchers have demonstrated that a dysfunctional placenta can play a formerly unknown role during the earliest phases of development in Cornelia de Lange.

17 Jun 2020

Loss of lipid-regulating protein drives prostate cancer metastasis

Johns Hopkins Kimmel Cancer Center researchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified a lipid-regulating protein that conveys what the researchers describe as "superpowers" onto prostate cancer cells, causing them to aggressively spread.

17 Jun 2020

New mechanism shows promise for treating certain congenital disorders

Scientists have discovered a major mechanism in the inactivation of X chromosomes, an event that may hold clues to develop treatments for congenital disorders.

16 Jun 2020

New X-ray technique reveals inner architecture of human bones

An international research team has used new X-ray techniques to describe how the architecture of healthy human bones is built up. The team has uncovered a hitherto unknown structure in healthy bones.

16 Jun 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020