Molecular & Structural Biology

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New mutation in common flu subtype helps evade immune response

Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

13 Jul 2020

New study may lead to advanced treatments for infections

Scientists from the University of Queensland have successfully solved a five-decade-old mystery that may lead to sophisticated herbicides and treatments for infections.

13 Jul 2020

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

UVA scientists shed light on how plants create cellulose for strength and growth

New research from the University of Virginia School of Medicine reveals how plants create the load-bearing structures that let them grow – much like how building crews frame a house.

13 Jul 2020

Scientists develop new genome editing methods for better crop yield

Although crop hybrid technologies have played a key role in considerably improving crop yield across the world in the past decades, developing and maintaining a hybrid production line has invariably been laborious and complex.

13 Jul 2020

Study identifies a new target for cancer treatment

Planar cell polarity (PCP) is a kind of process where polarization of the epithelial tissues occurs inside the plane of the epithelium. This process plays a significant role in the development and function of organs.

13 Jul 2020

Study may provide a therapeutically safer strategy for gene editing

The CRISPR gene editing system is a robust tool specifically developed for the targeted editing of genomes. While this tool has considerable therapeutic potential, it is associated with improper editing of “off-target” sites.

13 Jul 2020

X-ray method helps track protein folding

Researchers from the Korea Advanced Institute of Science and Technology (KAIST) have employed an X-ray technique to monitor the mechanism of protein folding.

13 Jul 2020

Researchers identify a new role for covalent linker involved in biological ion channel

Ion channels are essentially passageways through membranes that transport signals to a cell’s environment and enable it to respond.

13 Jul 2020

Study: PINK1 and Parkin work together to induce selective autophagy

Researchers at TMIMS have revealed that PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria to induce selective autophagy called mitophagy.

10 Jul 2020

Study explains why human mitochondrial genomes mutate frequently

One could say that mitochondria, the energy-producing organelles inside every human cell, dance to their own beat.

10 Jul 2020

TMEM106B gene reveals the causes of neurodegenerative diseases

Across the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal lobar degeneration (FTLD), which develop when neurons in specific parts of the brain stop functioning - triggering memory loss and other behavioral or personality changes.

10 Jul 2020

Study: Deep-sea microbes could have large amounts of available energy

Microbial cells are found in abundance in marine sediments beneath the ocean and make up a significant amount of the total microbial biomass on the planet.

10 Jul 2020

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

In a recent study of genes involved in brain functioning, their previously unknown features have been uncovered by bioinformaticians from the Moscow Institute of Physics and Technology and the Institute of Mathematical Problems of Biology, RAS. The findings are reported in PLOS One.

10 Jul 2020

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre at the University of Saskatchewan and Temple University have demonstrated that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals.

10 Jul 2020

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution

Researchers at the Francis Crick Institute have characterized the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform vaccine design.

10 Jul 2020

Study shows an entirely new complexity within enzyme machinery

Proteins are the workers in a cell and, as the "basic element of life", are responsible for the most widely varying metabolic processes.

9 Jul 2020

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

Chinese researchers recently discovered a protein quality control mechanism called "reubiquitination".

9 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

New spatial mapping method pinpoints new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

9 Jul 2020

Molecular & Structural Biology

New mutation in common flu subtype helps evade immune response

New study may lead to advanced treatments for infections

New drug enables the immune system to attack ovarian cancer, TGen study shows

UVA scientists shed light on how plants create cellulose for strength and growth

Scientists develop new genome editing methods for better crop yield

Study identifies a new target for cancer treatment

Study may provide a therapeutically safer strategy for gene editing

X-ray method helps track protein folding

Researchers identify a new role for covalent linker involved in biological ion channel

Study: PINK1 and Parkin work together to induce selective autophagy

Study explains why human mitochondrial genomes mutate frequently

TMEM106B gene reveals the causes of neurodegenerative diseases

Study: Deep-sea microbes could have large amounts of available energy

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution

Study shows an entirely new complexity within enzyme machinery

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

New type of molecular editor can make precise changes in mitochondrial DNA

New spatial mapping method pinpoints new potential therapeutic targets for lupus

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