Molecular & Structural Biology

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Deep learning can generate real insights into how proteins interact

Scientist are now combining recent advances in evolutionary analysis and deep learning to build three-dimensional models of how most proteins in eukaryotes interact.

23 Nov 2021

Researchers develop artificial genomic DNA capable of replication and evolution

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using cell-free materials alone, such as nucleic acids and proteins for the first time.

22 Nov 2021

Research findings anticipated to facilitate production of novel drug candidates

Pharmaceuticals commonly available on the market are developed by linking together rings of molecules to generate drugs that treat conditions like depression.

19 Nov 2021

New group of molecules that have an antibacterial effect identified

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria.

18 Nov 2021

Research demonstrates how diet affects immunity through the gut microbiome

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

From Harvard Medical School 17 Nov 2021

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

Study uncovers how brain cells encode head motion to enable navigation during the day and night

To navigate successfully in an environment, you need to continuously track the speed and direction of your head, even in the dark.

From University College London 17 Nov 2021

Researchers analyze patterns of rice adaptation to drought tolerance

Rice is not only a staple food but also a means of livelihood for numerous smallholder farmers in South and Southeast Asia.

17 Nov 2021

Study analyzes electrostatic interactions of proteins in Escherichia coli

Electrostatic interaction is significant for numerous biological reactions—like protein-protein interaction, enzyme catalysis, and H+ transfer.

17 Nov 2021

New gene critical for daily behavioral rhythms discovered

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type.

16 Nov 2021

Study provides strong evidence for 2,000-year-old sustainable Indigenous fishing practices

Ancient Indigenous fishing practices can be used to inform sustainable management and conservation today, according to a new study from Simon Fraser University.

15 Nov 2021

Research details how HIV-infected cells evade detection by the immune system

Scientists from the Wistar Institute revealed how major features on the surface of HIV-infected cells help the disease avoid detection by the immune system.

15 Nov 2021

Study shows how a common gene mutation robs people of natural cancer protection

Scientists from the University of Virginia School of Medicine have identified how a common gene mutation deprives people of natural protection against cancer.

15 Nov 2021

Study identifies molecular changes in red blood cells that cause vascular damage in type 2 diabetes

In type 2 diabetes, the modified function of the red blood cells causes vascular damage.

15 Nov 2021

Research establishes a new understanding of how DNA methylation begins in plants

Crop improvement often involves the transfer of genetic material from one organism to another to produce a valuable trait. Some major examples of crops with these so-called "transgenes" include disease-resistant cotton and beta-carotene-enhanced golden rice.

10 Nov 2021

Cancer invasion and migration can be suppressed by manipulating stiffness of cell membrane

A research collaboration has found that cancer invasion and migration in mice can be inhibited by controlling the stiffness of the cell membrane.

10 Nov 2021

Novel technique enhances the predictability of protein manufacturing

Researchers from VIB and Ghent University devised a new technique to analyze the secretability of hundreds of thousands of protein sequences at once.

10 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Experts determine the molecular structure of a gut protein

Researchers from EMBL Hamburg and the Centre for Structural Systems Biology (CSSB) identified the molecular structure of a gut protein that aids the absorption of various drugs. This finding can help produce drugs that reach target tissues more effectively.

8 Nov 2021

New technique to design enzyme stereoselectivity and substrate acceptance

Professor Zhoutong Sun headed a research team to develop Proline Induced Loop Engineering Test (PiLoT) method.

8 Nov 2021

Molecular & Structural Biology

Deep learning can generate real insights into how proteins interact

Researchers develop artificial genomic DNA capable of replication and evolution

Research findings anticipated to facilitate production of novel drug candidates

New group of molecules that have an antibacterial effect identified

Research demonstrates how diet affects immunity through the gut microbiome

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

Study uncovers how brain cells encode head motion to enable navigation during the day and night

Researchers analyze patterns of rice adaptation to drought tolerance

Study analyzes electrostatic interactions of proteins in Escherichia coli

New gene critical for daily behavioral rhythms discovered

Study provides strong evidence for 2,000-year-old sustainable Indigenous fishing practices

Research details how HIV-infected cells evade detection by the immune system

Study shows how a common gene mutation robs people of natural cancer protection

Study identifies molecular changes in red blood cells that cause vascular damage in type 2 diabetes

Research establishes a new understanding of how DNA methylation begins in plants

Cancer invasion and migration can be suppressed by manipulating stiffness of cell membrane

Novel technique enhances the predictability of protein manufacturing

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Experts determine the molecular structure of a gut protein

New technique to design enzyme stereoselectivity and substrate acceptance

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