Molecular & Structural Biology

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Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

A research team led by scientists from the Hong Kong University of Science and Technology has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.

20 Apr 2022

Molecular & Structural Biology

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

Double-stranded RNA provoke bone loss during periodontitis

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

A new breakthrough in the quest to improve photosynthesis in certain crops

Researchers analyze the complex function of cyanobacteria and the regulation of the biological clock

Max Planck researchers reveal the structure of kinetochore corona

Scientists gain fascinating insights into the dynamic ultrastructure of the heart

Researchers create RNA molecules to address human pancreatic beta cells

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

Researchers discover how an “accordion effect” is vital for switching off genes

Scientists recognize neuronal processes that regulate food cravings during pregnancy

Study discovers links between DNA methylation and gene expression in children

Novel method to obtain genomic data shows potential success

Certain RNA molecules may serve as markers of cellular stress in different diseases

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

Biologists unravel the mystery behind nuclear anomaly in blood cancer cells

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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