Molecular & Structural Biology

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Adolescents with higher omega-3 levels in blood are less likely to acquire psychotic illness

Adolescents who had greater levels of an omega-3 fatty acid in their blood were less likely to acquire psychotic illness in early adulthood.

3 Jun 2021

Researchers identify new therapeutic targets for flaviviruses

In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic targets.

2 Jun 2021

Understanding molecular determinants of liver cancer in patients with Indigenous American ancestry

Oncotarget published "Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry" which reported that contrasting with this pattern, the age structure of HCC in Andean people displays a bimodal distribution with half of the patients developing HCC in adolescence and early adulthood.

2 Jun 2021

Diet plays a crucial role in liver disease outcome, mouse model shows

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD patients are at higher risk of developing Non-alcoholic steatohepatitis (NASH), which causes severe and chronic liver inflammation, fibrosis and liver damage.

2 Jun 2021

Study discovers novel function for metabolic enzyme medium-chain acyl-CoA dehydrogenase

Scientists have come up with an innovative function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM).

1 Jun 2021

Researchers discover a new, effective way to treat aggressive blood cancer in children

Australian scientists have found what could prove to be a new and effective way to treat a particularly aggressive blood cancer in children.

31 May 2021

Study shows why “the brain's memory center” is vulnerable to damage, degeneration

In a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for why the area, commonly referred to as 'the brain's memory center', is vulnerable to damage and degeneration, a precursor to Alzheimer's disease.

31 May 2021

New wiki promotes development of innovative saliva-based diagnostic tests and customized treatment

The NIDCR has funded the creation of the Human Salivary Proteome Wiki, the first public platform that organizes information on each of the proteins found in human saliva.

27 May 2021

Study finds unique molecular mechanism by which Hepatitis C virus evades host’s immune system

Hepatitis C virus (HCV) can cause chronic liver infection, which can lead to irreparable liver damage and liver cancer.

From Osaka University 27 May 2021

Two components of bacterial CRISPR-Cas immunity system are physically linked

Skoltech scientists have demonstrated that the two components of the bacterial CRISPR-Cas immunity system are physically connected.

27 May 2021

Light-controlled on/off switch can help reset the biological clock

The biological clock is present in almost all cells of an organism. As more and more evidence emerges that clocks in certain organs could be out of sync, there is a need to investigate and reset these clocks locally.

26 May 2021

New method helps tests large groups for SARS-CoV-2 infection

Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.

25 May 2021

New genetic pathway plays a critical role in the ripening of tomatoes

An international research team has found that a genetic pathway known as CHLORAD, also plays a critical role in the ripening of tomatoes.

24 May 2021

Researchers gain new insights into the physiological functions of APP protein

The pivotal role played by the APP protein in Alzheimer’s disease is well known.

20 May 2021

Study: Turning off molecular switch could help treat melanoma

Melanoma accounts for only about 1% of skin cancers but leads to most of the skin cancer-related deaths.

20 May 2021

Researchers develop an unprecedentedly flexible new DNA staining probe

A team of scientists at Nagoya University in Japan has invented an extremely versatile DNA fluorescent dye called “Kakshine".

17 May 2021

New probe allows real-time imaging of molecular orientations in live cells

Monitoring alignments of the building blocks of cells is important to understand how the cells are built. By collaborating with imaging scientists at the MBL, researchers from Japan have developed a new probe which they call POLArIS, allowing real-time imaging of molecular orientations in live cells.

17 May 2021

Molecular & Structural Biology

Adolescents with higher omega-3 levels in blood are less likely to acquire psychotic illness

Researchers identify new therapeutic targets for flaviviruses

Understanding molecular determinants of liver cancer in patients with Indigenous American ancestry

Diet plays a crucial role in liver disease outcome, mouse model shows

Study discovers novel function for metabolic enzyme medium-chain acyl-CoA dehydrogenase

Researchers discover a new, effective way to treat aggressive blood cancer in children

Study shows why “the brain's memory center” is vulnerable to damage, degeneration

New wiki promotes development of innovative saliva-based diagnostic tests and customized treatment

Study finds unique molecular mechanism by which Hepatitis C virus evades host’s immune system

Two components of bacterial CRISPR-Cas immunity system are physically linked

Light-controlled on/off switch can help reset the biological clock

New method helps tests large groups for SARS-CoV-2 infection

New genetic pathway plays a critical role in the ripening of tomatoes

Researchers gain new insights into the physiological functions of APP protein

Study: Turning off molecular switch could help treat melanoma

Researchers develop an unprecedentedly flexible new DNA staining probe

New probe allows real-time imaging of molecular orientations in live cells

Scientists shed light on the origins of Mimivirus and other giant viruses

Study analyzes how resistance proteins defend plants from pathogens

Study reveals mitochondrial enzyme plays a vital role in preventing ferroptosis

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