Molecular & Structural Biology

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Novel computational tool integrates available biological data

The amount of biological data that is currently available has increased exponentially in recent decades as a result of the quick development of the various disciplines in the fields of biological and biomedical research (like genomics, proteomics, and transcriptomics).

16 Sep 2022

Study provides insight into how birds decide their sex

A study team has examined chicken germ cells using RNA-sequencing to anticipate the mechanism that determines the sex to better understand the process of the sex determination in the germ cell.

12 Sep 2022

Light-sensitive molecule can interpret moonlight to synchronize the reproductive cycles of marine life

How animals are able to interpret natural light sources to adjust their physiology and behaviour is poorly understood.

12 Sep 2022

Iron-sulfur cofactors are moved with the help of glutathione, experts reveal

The creation and movement of an essential class of molecules in human cells are now better understood according to a recent study.

8 Sep 2022

Spaceflight increases the risk of developing cancer and heart disease

A groundbreaking study from the Icahn School of Medicine at Mount Sinai found that astronauts are more likely to experience mutations that could be connected to spaceflight and increase their lifetime risk of acquiring cancer and heart disease.

2 Sep 2022

Therapeutic mRNAs do not significantly impact translational fidelity

Synthetic mRNA therapeutics for the treatment and prevention of disease has attracted a lot of interest due to the exceptional efficacy of mRNA vaccinations against SARS-CoV-2.

30 Aug 2022

Understanding protein structures can be more complicated than thought

When you think of proteins – the enzymes, signaling molecules, and structural components in every living thing – you might think of single strands of amino acids, organized like beads on a string.

29 Aug 2022

The correlation between high facial similarity and shared DNA

DNA analysis and a collection of photographs of genetically unrelated lookalikes have shown that strong facial likeness is tied to shared genetic variations. The article is published in Cell Reports on August 23rd, 2022.

25 Aug 2022

The complex link between pancreatic malformations and the “dark genome”

For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.

25 Aug 2022

Diseased connective tissue cells alter the physical structure of their genomes

Researchers at Penn Medicine have found that when cells are impacted by the disease, the physical structure of their genome changes.

25 Aug 2022

New technique reveals how environmental changes affect the dynamic structures of RNAs in living cells

The impact of environmental conditions on the dynamic structures of RNAs in living cells has been revealed by innovative technology developed by researchers at the John Innes Centre.

18 Aug 2022

Researchers face challenges with stem cell lines that carry major DNA damage

Stem cells are a type of cell that can be configured to transform into almost any sort of cell in the body. They are presently used in research on organ development as well as in the initial phases of embryo development.

15 Aug 2022

Researchers determine a novel antiviral technique to combat bacteria

Bacteria use a wide range of defense strategies to combat viral infection, and some of these systems have resulted in game-changing technologies like CRISPR-based gene editing.

From Massachusetts Institute of Technology (MIT) 15 Aug 2022

Fabimycin likely to be an effective treatment for drug-resistant bacteria

Bacteria that cause urinary tract infections are getting more and more resistant to many medications, and they are becoming more and more difficult to cure.

12 Aug 2022

Banp indispensable for cell-cycle progression and cell survival

Zebrafish mutants were found by a team of researchers about 15 years ago. These zebrafish’s eyes did not mature properly, which explains why they are much smaller than the eyes of zebrafish found in the wild.

11 Aug 2022

Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

An antibody that is successfully used to treat a variety of tumors has been replaced with a tiny molecule that researchers from Tel Aviv University and the University of Lisbon have jointly found and manufactured.

9 Aug 2022

Mitochondrial DNA plays a crucial role in inflammation, study finds

Mitochondria are generally known as the powerhouse of the cell, however, growing research indicates that they may potentially be involved in inflammation.

8 Aug 2022

Scientists solve how RNA molecules reach their targets

Scientists claim that life does not come with an instruction manual, but this is not totally accurate. Each cell in our body follows the instructions provided by its DNA in the form of RNA molecules.

1 Aug 2022

A Retro-Cascorder device records a cell’s genetic activity in DNA for days at a time

If you want to keep track of someone’s activities for a day, contact them every 10 minutes and inquire what they are up to. It would be simpler, though, to equip them with a journal in which to record their own acts.

1 Aug 2022

Study shows how two matching DNA strands hybridize to generate double-stranded DNA

Nanoscientists and theoretical physicists from UNSW Medicine & Health’s EMBL Australia Node in Single Molecule Science collaborated to decipher the intricate mechanics of determining how quickly two matched strands of DNA may completely come together—or hybridize—to generate double-stranded DNA. Their results were reported in Nucleic Acids Research.

From The University of New South Wales (UNSW) 28 Jul 2022