Molecular & Structural Biology

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Researchers create world's smallest mechanically interlocked biological structure

Researchers at Princeton University have built the world's smallest mechanically interlocked biological structure, a deceptively simple two-ring chain made from tiny strands of amino acids called peptides.

25 Aug 2021

Study unravels new aspects of prions causing untreatable neurodegenerative conditions

A new study achieved the highest-ever resolution imaging of an infectious prion, offering atomic-level data of how these abnormal proteins assemble.

25 Aug 2021

Researchers use DNA barcoding to authenticate 'wild mushrooms' in food products

Harvesting wild mushrooms requires an expert eye to distinguish between the delicious and the inedible. Misidentification can have a range of consequences, from a disgusting taste and mild illness to organ failure and even death.

From The University of Utah 24 Aug 2021

Genome editing tool used to render male mosquitoes infertile and slow disease spread

Mosquitos spread viruses that cause potentially deadly diseases such as Zika, dengue fever and yellow fever. New U.S. Army-funded research uses gene editing to render certain male mosquitoes infertile and slow the spread of these diseases.

24 Aug 2021

Scientists isolate monoclonal antibodies against alphaviruses

A research group has isolated monoclonal antibodies that, in laboratory and animal studies, prohibited infection by alphaviruses.

From Vanderbilt University 24 Aug 2021

Study finds the link between circular RNA and alternative splicing in gastric cancer

At the Chinese Academy of Sciences, scientists have now come up with a mechanism used by circular RNA to inhibit the metastasis of gastric cancer cells.

23 Aug 2021

Study discovers Parkinson’s disease-linked protein impairs mitochondria

Recently, researchers discovered that a protein linked with Parkinson’s disease can impair mitochondria.

23 Aug 2021

Researchers discover how glycans act as gateways for SARS-CoV-2 entry

Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter and infect healthy human cells.

From UC San Diego 20 Aug 2021

New mouse line reveals the state of proteostasis in mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

From UC San Diego 20 Aug 2021

Study reveals how two separate DNA changes may predict aggressive childhood leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination.

From The University of Utah 20 Aug 2021

New research identifies a master timekeeper for the brain's circadian clock

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain's circadian clock, new research led by UT Southwestern scientists suggests.

20 Aug 2021

Novel genome-editing technology to mitigate Alzheimer’s disease

Around 500,000 patients in China alone are considered to be living with a hereditary form of Alzheimer’s disease (AD).

19 Aug 2021

Study identifies gene families responsible for simple leaf development

Recent research elucidates how simple leaves—one of the two basic forms of leaves—originate in a plant.

18 Aug 2021

Insect olfaction could be used to help develop drug screening techniques

Scientists investigated a key element of the insect olfactory system to analyze how this insight might help humans.

18 Aug 2021

Researchers modify CRISPR to enable antibody-based medical diagnostics

Researchers adapted CRISPR to analyze antibodies in patient blood samples to pave the way for a new class of medical diagnostics.

From Harvard Medical School 16 Aug 2021

Scientists take step to engineer crops with higher yields by improving photosynthesis

In order to feed a projected 9 billion people by 2050, farmers need to grow 50% more food on a limited amount of arable land. As a result, plant scientists are in a race against time to engineer crops with higher yields by improving photosynthesis.

16 Aug 2021

Researchers identify new technique to measure DNA torsional stiffness

Cornell researchers have identified a new way to measure DNA torsional stiffness – how much resistance the helix offers when twisted – information that can potentially shed light on how cells work.

16 Aug 2021

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

The single-stranded genetic material RNA is best known for guiding the assembly of proteins in our cells and carrying the genetic code for viruses like SARS-CoV-2 and HIV.

16 Aug 2021

Study reveals how 3D space is represented in the mammalian cortex by the brain's 'GPS'

In a new study published in Nature today, Weizmann Institute of Science researchers, in collaboration with colleagues from the Hebrew University of Jerusalem, unveiled for the first time how three-dimensional space is represented in the mammalian cortex by the brain's "GPS" system.

13 Aug 2021

Molecular & Structural Biology

Researchers create world's smallest mechanically interlocked biological structure

Study unravels new aspects of prions causing untreatable neurodegenerative conditions

Researchers use DNA barcoding to authenticate 'wild mushrooms' in food products

Genome editing tool used to render male mosquitoes infertile and slow disease spread

Scientists isolate monoclonal antibodies against alphaviruses

Study finds the link between circular RNA and alternative splicing in gastric cancer

Study discovers Parkinson’s disease-linked protein impairs mitochondria

Researchers discover how glycans act as gateways for SARS-CoV-2 entry

New mouse line reveals the state of proteostasis in mammalian brain for the first time

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

Study reveals how two separate DNA changes may predict aggressive childhood leukemias

New research identifies a master timekeeper for the brain's circadian clock

Novel genome-editing technology to mitigate Alzheimer’s disease

Study identifies gene families responsible for simple leaf development

Insect olfaction could be used to help develop drug screening techniques

Researchers modify CRISPR to enable antibody-based medical diagnostics

Scientists take step to engineer crops with higher yields by improving photosynthesis

Researchers identify new technique to measure DNA torsional stiffness

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

Study reveals how 3D space is represented in the mammalian cortex by the brain's 'GPS'

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