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Novel targeted therapy blocks critical metabolic pathways in cancer cells

Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.

24 Nov 2020

Study shows how drug-like small molecules regulate the activity of ion channels

Researchers have recently discovered how the function of therapeutically relevant ion channels is regulated by drug-like small molecules.

24 Nov 2020

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Scientists have successfully utilized a novel stem cell technology to examine the skin, specific to a group of living patients, in laboratory settings.

24 Nov 2020

Measurement of Cancer Biomarker Enrichment in Exosomes

Postnova Analytics reports that researchers from the University of Utah (Salt Lake City, USA) have used a novel combination of Asymmetrical Flow Field-Flow Fractionation and Centrifugal Field-Flow Fractionation to measure cancer biomarker enrichment in exosomes.

From Postnova Analytics 24 Nov 2020

COVID-19 pandemic has considerably affected the U.S. seafood industry, shows study

The United States' seafood industry declined precipitously in the months following the emergence of the COVID-19 pandemic, and research shows that targeted federal assistance will be necessary to bring it back.

24 Nov 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Researchers look for mechanisms that stabilize or destabilize key sections of biomolecules

Knowing precisely where proteins are frustrated could go a long way toward making better drugs. That's one result of a new study by Rice University scientists looking for the mechanisms that stabilize or destabilize key sections of biomolecules.

24 Nov 2020

Researchers evaluate effectiveness of conservation efforts to save endangered species

New research from the University of Stirling into the effectiveness of international conservation projects could help to save endangered species from extinction.

24 Nov 2020

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

An international research alliance has visualized the RNA folding structures of the SARS-CoV-2 genome, for the first time.

23 Nov 2020

Plant used in traditional Chinese medicine becomes less visible to humans

According to a new study, a plant utilized in traditional Chinese medicine has emerged to become less perceptible to human beings.

From University of Exeter 23 Nov 2020

Researchers use metal-organic frameworks to target prostate cancer cells

Scientists have used metal-organic frameworks to effectively deliver the CRISPR/Cas9 genetic snipping tool into human cancer cells.

23 Nov 2020

Architecture of cell nucleus can change gene activity in plants

Scientists from the University of Tokyo have learned how the layout of the cell nucleus can alter the activity of genes found in plants.

23 Nov 2020

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

A genetic modification in the 'coat' of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers.

23 Nov 2020

First functional analysis of cytokine IL-15L using rainbow trout

The cytokine family including interleukin-2 and -15 (IL-2 and IL-15) started out in a primitive vertebrate species with three related cytokines IL-2, IL-15, and IL-15-like (IL-15L), all sharing binding capacity for receptor chain IL-15Rα. IL-15L was conserved in fishes, reptiles, and some mammals but lost in humans and mice.

23 Nov 2020

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

A genetic modification in the 'coat' of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers.

23 Nov 2020

WSU researchers develop new approach to classify the ocean's diverse environments

Washington State University scientists have developed a new way to classify the ocean's diverse environments, shedding new light on how marine biomes are defined and changed by nature and humans.

23 Nov 2020

Adipose tissue plays key role in the aggravation of COVID-19

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

23 Nov 2020

Research sheds light on T cell abnormality in critically ill COVID-19 patients

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients.

23 Nov 2020

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but an Ludwig-Maximilians-Universitaet (LMU) in Munich team now reports that ribosome assembly in human cells requires factors that have no counterparts in simpler model organisms.

23 Nov 2020

Biologists unravel how tissue geometry influences cell migration

Cells move constantly throughout our bodies, performing myriad operations critical to tissue development, immune responses, and general wellbeing. This bustle is guided by chemical cues long studied by scientists interested in cellular migration.

23 Nov 2020

Life Science News

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Study shows how drug-like small molecules regulate the activity of ion channels

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Measurement of Cancer Biomarker Enrichment in Exosomes

COVID-19 pandemic has considerably affected the U.S. seafood industry, shows study

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Researchers look for mechanisms that stabilize or destabilize key sections of biomolecules

Researchers evaluate effectiveness of conservation efforts to save endangered species

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

Plant used in traditional Chinese medicine becomes less visible to humans

Researchers use metal-organic frameworks to target prostate cancer cells

Architecture of cell nucleus can change gene activity in plants

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

First functional analysis of cytokine IL-15L using rainbow trout

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

WSU researchers develop new approach to classify the ocean's diverse environments

Adipose tissue plays key role in the aggravation of COVID-19

Research sheds light on T cell abnormality in critically ill COVID-19 patients

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Biologists unravel how tissue geometry influences cell migration

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