Dementia News and Research

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Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

24 Mar 2021

Processed meat consumption associated with increased risk of dementia

Scientists from the University of Leeds's Nutritional Epidemiology Group used data from 500,000 people, discovering that consuming a 25g serving of processed meat a day, the equivalent to one rasher of bacon, is associated with a 44% increased risk of developing the disease.

23 Mar 2021

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

10 Mar 2021

Two new Alzheimer’s genes discovered

AZoLifeSciences speaks to researchers from Tianjin Medical University about their latest research that led to the discovery of two new genes that are linked to Alzheimer's disease.

From Tianjin Medical University 1 Mar 2021

New signaling pathway prevents the overproduction of RNA-protein complexes

Neurodegenerative diseases, such as various forms of senile dementia or amyotrophic lateral sclerosis (ALS), have one thing in common: large amounts of certain RNA-protein complexes (snRNPs) are produced and deposited in the nerve cells of those affected - and this hinders the function of the cells.

26 Feb 2021

Neuronal and glial circuits form loosely coupled super-network within the brain

Tohoku University scientists have shown that neuronal and glial circuits form a loosely coupled super-network within the brain.

25 Feb 2021

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

From UC San Diego 19 Feb 2021

Ancestral backgrounds can influence Alzheimer's disease risk, finds study

Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele.

5 Feb 2021

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.

27 Jan 2021

Researchers discover genetic risk factor for stroke

A research team from Geisinger Health System has detected a common genetic variant as a risk factor for stroke, particularly in patients aged more than 65.

20 Jan 2021

Study shows how AFV3-109 protein with slipknot structure folds and unfolds based on temperature

Scientists from the Pacific Quantum Center of Far Eastern Federal University (FEFU) figured out how the AFV3-109 protein with slipknot structure folds and unfolds depending on temperature. The protein is typical for the viruses of the oldest single-celled organisms that can survive in the extreme conditions of underwater volcanic sources - archaea. The research outcome appears in PLOS ONE.

15 Jan 2021

KAIST researchers identify mechanism underlying plasticity in adult brains

Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away.

28 Dec 2020

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

The research group led by Dr Sjoerd van Wijk from the Institute of Experimental Cancer Research in Paediatrics at Goethe University already two years ago found evidence indicating that the anti-diarrhea drug loperamide could be used to induce cell death in glioblastoma cell lines.

23 Dec 2020

New model shows how the brain uses "gating" phenomenon to control information

Getting computers to "think" like humans is the holy grail of artificial intelligence, but human brains turn out to be tough acts to follow. T

17 Dec 2020

Study examines impacts of widespread ocean pollution on human health

Ocean pollution is widespread and getting worse, and when toxins in the oceans make landfall they imperil the health and well-being of more than 3 billion people, according to a new report by an international coalition of scientists led by Boston College's Global Observatory on Pollution on Health and the Centre Scientifique de Monaco, supported by the Prince Albert II of Monaco Foundation.

4 Dec 2020

Researchers identify promising treatments for late-onset Alzheimer’s disease

Scientists from The Mount Sinai Hospital and the National Center for Geriatrics and Gerontology based in Japan have recently discovered novel molecular mechanisms that drive late-onset Alzheimer’s disease (LOAD).

25 Nov 2020

Tau protein in Alzheimer's disease looks different at every dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

Dementia News and Research

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Processed meat consumption associated with increased risk of dementia

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

Two new Alzheimer’s genes discovered

New signaling pathway prevents the overproduction of RNA-protein complexes

Neuronal and glial circuits form loosely coupled super-network within the brain

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Ancestral backgrounds can influence Alzheimer's disease risk, finds study

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Researchers discover genetic risk factor for stroke

Study shows how AFV3-109 protein with slipknot structure folds and unfolds based on temperature

KAIST researchers identify mechanism underlying plasticity in adult brains

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

New model shows how the brain uses "gating" phenomenon to control information

Study examines impacts of widespread ocean pollution on human health

Researchers identify promising treatments for late-onset Alzheimer’s disease

Tau protein in Alzheimer's disease looks different at every dementia stage

Study shows how air pollution exposures affect mental health later in life

Study confirms correlation between gut microbiota and Alzheimer's disease

Researcher develops procedures for defining preclinical stages of Alzheimer's disease

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