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Inflammation-Induced Epigenetic Changes Limit Intestinal Stem Cell Regeneration

Researchers from the University of Michigan, Baylor College of Medicine, and other affiliated institutions have found that intestinal stem cells (ISCs) are permanently altered by inflammation in the gut, which limits the cells' capacity to repair the gut even after the inflammation has subsided.

4 Sep 2024

Beta Cells Alone Can Maintain Glycemic Balance Without Other Pancreatic Cells

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels.

4 Sep 2024

Genetic Variants Linked to Rare Bicuspid Aortic Valve Disease Identified

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

3 Sep 2024

Melbourne Researchers Achieve Breakthrough in Creating Human-Like Blood Stem Cells

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body.

3 Sep 2024

Single-Cell Sequencing Reveals Mechanism of Coronary Artery Formation

The process by which new arteries develop in the heart has been clarified by a group under the direction of Dr. Elena Cano at the Integrative Vascular Biology Lab of Professor Holger Gerhardt at the Max Delbrück Center in Berlin.

2 Sep 2024

Study Identifies Genes for Healthier Rice with Low Glycemic Index and High Protein

A team of researchers at the International Rice Research Institute (IRRI) has identified genes and markers responsible for low glycemic index (GI) and high protein content in rice, using genetics and artificial intelligence classification methods.

2 Sep 2024

New Insights into Mosquito Mating Could Enhance Malaria Control Strategies

A high-pitched buzzing sound in your ear is an unmistakable sign that a female mosquito is out on the hunt -; for they, not males, drink blood. Hearing that tone might make you turn to try to swat the pest. But for a male mosquito, that tone means it's time to mate.

2 Sep 2024

Marmosets Use Vocal Calls to Name Each Other, Study Reveals

In a groundbreaking discovery, researchers from Hebrew University have found that marmoset monkeys use specific vocal calls, called "phee-calls," to identify and communicate with each other. This ability to vocally label others has only been seen in humans, dolphins, and elephants until now.

30 Aug 2024

Evolution of Blood Sugar Regulation in Neotropical Bats

Humans must regulate blood sugar concentrations to stay healthy and to fuel our cells. Too little or too much can cause serious health complications, and high blood sugar is a hallmark of the metabolic condition, diabetes. New research from the Stowers Institute for Medical Research may enable potential solutions to metabolic disease by turning to evolution and to bats.

29 Aug 2024

Clock Genes Drive Evolutionary Split in Two Moth Species

Investigating moth speciation, this research highlights the impact of clock genes on behavior, providing a rare glimpse into evolutionary processes.

28 Aug 2024

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Research on intestinal immuno-organoids reveals their potential in modeling immune interactions and studying intestinal diseases linked to cancer therapies.

26 Aug 2024

Study Identifies Key Macrophage Subpopulations in MASH Progression and Regression

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

23 Aug 2024

New Research Reveals Infrared Radiation as a Mosquito Host-Seeking Trigger

While a mosquito bite is often no more than a temporary bother, in many parts of the world it can be scary. One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika, and other diseases every year. Another, Anopheles gambiae, spreads the parasite that causes malaria. The World Health Organization estimates that malaria alone causes more than 400,000 deaths every year. Indeed, their capacity to transmit disease has earned mosquitoes the title of deadliest animal.

23 Aug 2024

Mitochondrial DNA 'Jumps' to Chromosomes, Potentially Impacting Lifespan

As direct descendants of ancient bacteria, mitochondria have always been a little alien.

23 Aug 2024

Efficient and Reproducible BBB Modeling for Drug Development

Scientists at Southwest Research Institute have developed a new screening method to identify drug formulations that can penetrate the blood-brain barrier (BBB), to facilitate treatment of brain diseases and conditions.

23 Aug 2024

Scientists Discover How AML Cells Use P-Bodies to Sustain Growth

An international team of scientists has uncovered a mechanism by which acute myeloid leukemia (AML) cells sustain their growth.

22 Aug 2024

Mother's Gut Microbiome Key to Baby's Brain Development

A study in mice has discovered that the presence of Bifidobacterium breve bacteria in the mother's gut during pregnancy promotes healthy brain development in the fetus.

22 Aug 2024

Discovery of Ancient Stem Cells in Sea Anemones Offers Clues to Immortality and Regeneration

The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time.

20 Aug 2024

Breakthrough Research Reveals Early Development of Eye Macrophages in Mice

Macrophages, also known as scavenger cells, are part of our immune system. They destroy invading pathogens and are found in the organs and the bloodstream.

20 Aug 2024

Study Uncovers Biomarkers for Low Muscle Mass, Offering Insights for Personalized Prevention

Machine learning models to analyze computed tomography (CT) images of the chest and a proteomics approach to determine blood protein biomarkers.

15 Aug 2024

Blood News and Research

Inflammation-Induced Epigenetic Changes Limit Intestinal Stem Cell Regeneration

Beta Cells Alone Can Maintain Glycemic Balance Without Other Pancreatic Cells

Genetic Variants Linked to Rare Bicuspid Aortic Valve Disease Identified

Melbourne Researchers Achieve Breakthrough in Creating Human-Like Blood Stem Cells

Single-Cell Sequencing Reveals Mechanism of Coronary Artery Formation

Study Identifies Genes for Healthier Rice with Low Glycemic Index and High Protein

New Insights into Mosquito Mating Could Enhance Malaria Control Strategies

Marmosets Use Vocal Calls to Name Each Other, Study Reveals

Evolution of Blood Sugar Regulation in Neotropical Bats

Clock Genes Drive Evolutionary Split in Two Moth Species

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Study Identifies Key Macrophage Subpopulations in MASH Progression and Regression

New Research Reveals Infrared Radiation as a Mosquito Host-Seeking Trigger

Mitochondrial DNA 'Jumps' to Chromosomes, Potentially Impacting Lifespan

Efficient and Reproducible BBB Modeling for Drug Development

Scientists Discover How AML Cells Use P-Bodies to Sustain Growth

Mother's Gut Microbiome Key to Baby's Brain Development

Discovery of Ancient Stem Cells in Sea Anemones Offers Clues to Immortality and Regeneration

Breakthrough Research Reveals Early Development of Eye Macrophages in Mice

Study Uncovers Biomarkers for Low Muscle Mass, Offering Insights for Personalized Prevention

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

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