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Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Study shows lasting immunity offered by SARS-CoV-2 antibodies

One of the most significant questions about the novel coronavirus is whether people who are infected are immune from reinfection and, if so, for how long.

14 Oct 2020

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

Study could explain why some people are severely affected by Bardet-Biedl syndrome

Geneticists usually split disorders into “simple”, where mutations in several genes contribute modest quantities.

13 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

New computational biology algorithm may enable more effective cellular therapies

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders. But a major challenge for cell therapy applications is keeping cells alive and well in the lab.

13 Oct 2020

Scientists develop new antimicrobial molecules from toxic proteins in wasp venom

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

13 Oct 2020

Research focuses on understanding production of memory B cells and immune responses

The current COVID-19 climate has made vaccines, antibodies, and immune responses topics of everyday conversation. Now, it isn't just immunologists who want to know how our bodies respond to re-infections months, years, or sometimes decades after an initial immune response.

From Osaka University 13 Oct 2020

Gene variations that regulate dopamine levels may influence the mobility of elders

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

13 Oct 2020

Stem cells that promote bone repair can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

13 Oct 2020

Dopamine and serotonin found to be involved in perception, cognitive capacities

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals -- dopamine and serotonin -- are at work at sub-second speeds to shape how people perceive the world and take action based on their perception.

13 Oct 2020

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

It's one of the world's deadliest animals, and it has a taste for human blood: the mosquito. Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Severe cases of COVID-19 resemble systemic lupus erythematosus

Scientists from Emory Health Sciences have been observing an intense stimulation of immune cells in severe cases of COVID-19 disease. This activation of immune cells is similar to acute flares of systemic lupus erythematosus (SLE)—an autoimmune disease.

13 Oct 2020

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Volume 11, Issue 28 of Oncotarget features "Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation" by Gaba et, al. which reported that reliable development of Oncopig HCC cell lines was demonstrated through hepatocyte isolation and Cre recombinase exposure across 15 Oncopigs.

12 Oct 2020

Medicine News and Research

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Researchers unravel molecular factors that drive severity of COVID-19

Study shows lasting immunity offered by SARS-CoV-2 antibodies

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Study could explain why some people are severely affected by Bardet-Biedl syndrome

Treatment using immune system T cells preserves vision of mice with retinoblastoma

New computational biology algorithm may enable more effective cellular therapies

Scientists develop new antimicrobial molecules from toxic proteins in wasp venom

Research focuses on understanding production of memory B cells and immune responses

Gene variations that regulate dopamine levels may influence the mobility of elders

Stem cells that promote bone repair can also generate arthritic bone spurs

Dopamine and serotonin found to be involved in perception, cognitive capacities

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

Severe cases of COVID-19 resemble systemic lupus erythematosus

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Researchers test the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Developing a 'Trojan Horse' nanotherapy to fight breast cancer

Bone destruction caused by too little sugar

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

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