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Exploring cell and gene based therapies for Parkinson’s disease

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease on "Repairing the Parkinsonian Brain," experts highlight some of the current strategies being pursued to restore lost function and replace what is lost in the PD brain, with special emphasis on the challenges associated with translating advanced therapeutic approaches into pioneering clinical trials.

24 Sep 2021

Researchers identify host entry factor for Rift Valley fever virus

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle. These mosquito-borne outbreaks lead to infection in people working with dead or dying animals, sometimes causing hundreds of human cases and dozens of deaths.

24 Sep 2021

New map provides a reference to predict which antibodies are effective against SARS-CoV-2

Scientists at La Jolla Institute for Immunology have published a detailed map of where human antibodies bind to SARS-CoV-2, a map that was generated by a global collaboration comparing nearly all leading clinical candidates.

24 Sep 2021

Researchers report new route for artificial starch synthesis from carbon dioxide

Chinese scientists recently reported a de novo route for artificial starch synthesis from carbon dioxide (CO2) for the first time. Relevant results were published in Science on Sept. 24.

24 Sep 2021

Scientists analyze the molecular machinery of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

NIH to renew grants to continue building the ClinGen resource

In an effort to continue building the Clinical Genome Resource, the National Institutes of Health will be renewing three awards amounting to $73.2 million over five years.

From National Human Genome Research Institute (NHGRI) 24 Sep 2021

How do genetic variants influence the expression of genes in the blood?

Researchers are now pursuing intensive research on the genetic causes of traits and diseases, with over 250,000 such links known currently.

24 Sep 2021

How does the KLF4 transcription factor influence gene expression?

Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.

24 Sep 2021

Study seeks climate-smart strategies for root, tuber and banana crops in sub-Saharan Africa

Root, tuber and banana (RT&B) crops are widely cultivated across the landscapes of sub-Saharan Africa (SSA).

23 Sep 2021

Discovery may offer a promising new path for the study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Food insecurity increased early in the pandemic, mostly among families with children

Nearly 15 percent of U.S. households-;and nearly 18 percent of households with children-;reported food insecurity early in the COVID-19 pandemic, according to a survey conducted via social media by researchers at NYU School of Global Public Health.

From New York University (NYU) 23 Sep 2021

Researchers show how 'bad mucin' contributes to worsening pulmonary conditions

Mucus is an essential protective layer of gel-like liquid composed largely of proteins called mucins throughout our airways.

23 Sep 2021

Researchers develop a DNA sensor to target and detect infectious viruses in minutes

A new sensor can detect not only whether a virus is present, but whether it's infectious – an important distinction for containing viral spread.

23 Sep 2021

Microglial cells join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021

Research News and Research

Exploring cell and gene based therapies for Parkinson’s disease

Researchers identify host entry factor for Rift Valley fever virus

New map provides a reference to predict which antibodies are effective against SARS-CoV-2

Researchers report new route for artificial starch synthesis from carbon dioxide

Scientists analyze the molecular machinery of poxviruses at an atomic level

NIH to renew grants to continue building the ClinGen resource

How do genetic variants influence the expression of genes in the blood?

How does the KLF4 transcription factor influence gene expression?

Study seeks climate-smart strategies for root, tuber and banana crops in sub-Saharan Africa

Discovery may offer a promising new path for the study of multiple sclerosis

Food insecurity increased early in the pandemic, mostly among families with children

Researchers show how 'bad mucin' contributes to worsening pulmonary conditions

Researchers develop a DNA sensor to target and detect infectious viruses in minutes

Microglial cells join together to break down toxic proteins more quickly

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

High levels of sulfur volatiles in saliva make children dislike Brassica vegetables

Llamas' nanobodies could provide a new frontline treatment against Covid-19

Study explores the benefits of the MIND diet for older adults

Novel process for accurate data analysis from NMR spectrometers

Researchers reverse Kleefstra syndrome after birth in a mouse model

Analytical Chemistry - Industry Focus eBook eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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