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Heparin blocks SARS-CoV-2 infection in cell studies

In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.

27 Jul 2020

New technology can speed up drug development for tuberculosis

A novel technology that integrates machine learning and high-throughput imaging could accelerate drug discovery to fight tuberculosis (TB).

27 Jul 2020

Coronavirus changes structure that prevents cells from detecting it

With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.

24 Jul 2020

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Epigenomic data can help characterize genes that play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

From Massachusetts Institute of Technology (MIT) 24 Jul 2020

Study shows how the immune system attacks harmful viruses and bacteria

A new study has revealed how immune cells migrate to the lymph nodes and help attack harmful viruses and bacteria.

23 Jul 2020

Study reveals the degradation mechanism of endoplasmic reticulum

A team of researchers have analyzed the degradation mechanism of the endoplasmic reticulum (ER) called ER-phagy.

23 Jul 2020

Reactivating divergent signaling pathways to enhance cancer treatment

In order for cancer to form in the human body, normal cells must acquire multiple mutations before they develop toward the disease. It was previously believed that these mutations acted in concert in the progression of cancer.

23 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Researchers recreate pancreatic tissue 'in vitro' using 3D cell culture technique

Pancreatic cancer is a life-threatening disease with very poor survival rates in patients, and--despite various efforts--its treatment remains challenging.

23 Jul 2020

New pathways that could help treat RNA viruses discovered

Researchers at the University of New Hampshire have identified new pathways in an RNA-based virus where inhibitors, like medical treatments, unbind.

23 Jul 2020

Simple DNA repeats can be the basis for genetic computers

Dr. Herbert asks what if our genome was far smarter than everyone previously believed? What if in the many DNA repeat elements lay the foundation for building a novel type of biocomputer?

22 Jul 2020

Study reveals key factor that influences malignant cells to develop into tumor

Researchers have unraveled a crucial factor that governs whether malignant cells will develop into a tumor. The study was recently published in the eLife journal.

22 Jul 2020

Fasting-mimicking diet combined with hormone therapy has potential to treat breast cancer

A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans.

22 Jul 2020

Study explores the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Hybrid virus infects cells, interacts with antibodies just like COVID-19 virus

Airborne and potentially deadly, the virus that causes COVID-19 can only be studied safely under high-level biosafety conditions.

22 Jul 2020

Quality of lab procedures has a big impact on discovery of effective drugs

In their quest to find new drugs to treat deadly diseases, scientists study millions of molecules at high speed at the same time. Often it is enzymes that are investigated as targets in these 'high-throughput' screenings.

From University of Bath 22 Jul 2020

Researchers image the formation of four-stranded DNA in living human cells

The development of four-stranded DNA has been monitored in the living cells of human beings, enabling researchers to observe its potential role in cancer.

21 Jul 2020

Newly discovered protein could be an important target to prevent prostate cancer metastases

Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.

21 Jul 2020

Drugs News and Research

Heparin blocks SARS-CoV-2 infection in cell studies

New technology can speed up drug development for tuberculosis

Coronavirus changes structure that prevents cells from detecting it

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

Study shows how cancer develops resistance to chemotherapy

Epigenomic data can help characterize genes that play key role in cancer progression

Study shows how the immune system attacks harmful viruses and bacteria

Study reveals the degradation mechanism of endoplasmic reticulum

Reactivating divergent signaling pathways to enhance cancer treatment

New startup launched to overcome the challenge of delivering next-generation therapeutics

Researchers recreate pancreatic tissue 'in vitro' using 3D cell culture technique

New pathways that could help treat RNA viruses discovered

Simple DNA repeats can be the basis for genetic computers

Study reveals key factor that influences malignant cells to develop into tumor

Fasting-mimicking diet combined with hormone therapy has potential to treat breast cancer

Study explores the genetic and molecular basis of PD-L2 regulation

Hybrid virus infects cells, interacts with antibodies just like COVID-19 virus

Quality of lab procedures has a big impact on discovery of effective drugs

Researchers image the formation of four-stranded DNA in living human cells

Newly discovered protein could be an important target to prevent prostate cancer metastases

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