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How Singing Mice Reveal the Roots of Vocal Communication

All mice squeak, but only some sing. Scotinomys teguina, aka Alston's singing mice, hail from the cloud forests of Costa Rica. More than 2,000 miles north, Cold Spring Harbor Laboratory (CSHL) neuroscientists study these musically gifted mammals to better understand the evolutionary origins of vocal communication.

2 Dec 2025

New Study Finds Higher Levels of Antimicrobial Resistance (AMR) in Surface Water During Winter

A new study from The James Hutton Institute, Scotland’s pre-eminent interdisciplinary scientific research institute for the sustainable management of land, crop and nature resources, has found that the levels of antimicrobial resistance (AMR) present in surface water increase during winter.

21 Nov 2025

Sabotaging T Cell Exhaustion for Cancer Therapy

Like all hardworking things, the cytotoxic T lymphocytes (CTLs) of the immune system charged with detecting and destroying cancer cells tend to get very tired-so much so, in fact, that they can even die from exhaustion.

18 Nov 2025

Warmer Temperatures Drive Faster Immune Responses Through Myosin II Activation

Temperature is a key physiological factor that determines the speed of immune reactions. While this may seem obvious, it has remained largely unexplored at the single-cell level-until now.

5 Nov 2025

Your Washing Machine Isn’t As Clean As You Think

Washing machines may harbor microbes linked to hygiene risks. Study reveals user-specific microbial profiles and the impact of machine design on contamination.

5 Nov 2025

Precision Genome Editing of D3 Gene Enhances Rice Architecture and Stress Resilience

By precisely editing the D3 gene, which regulates both plant height and tillering, researchers developed compact, high-tillering rice plants that maintain grain yield while showing enhanced resistance to bacterial blight.

30 Oct 2025

Unlocking the Secrets of Neural Ion Channels

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell-and the molecular gatekeepers that help control them.

30 Oct 2025

Breakthrough Cryo-EM Study Maps Herpes Replication Protein in New Detail

An international research team has successfully identified the initial high-resolution structures of the herpes simplex virus origin-binding protein (OBP), which is an essential element in viral DNA replication that has remained structurally uncharacterized for the past forty years.

24 Oct 2025

Scientists Reveal How Nanovaccines Boost the Immune Fight Against Aggressive Breast Cancers

Nanovaccines show promise in breast cancer therapy, enhancing immune activation and targeting cold tumors, particularly in challenging triple-negative cases.

24 Oct 2025

DNA Cassettes Enable Long-Lasting Antibody Production Directly Inside Patients

A multidisciplinary team of scientists led by The Wistar Institute, including Perelman School of Medicine at the University of Pennsylvania, AstraZeneca and Inovio Pharmaceuticals, published today in Nature Medicine a breakthrough in biologic antibody production that happens directly in human subjects in this encouraging first clinical trial of its kind.

23 Oct 2025

Understanding the Ecological Trap Threatening Winter-Ready Species

Even as autumn days grow shorter, a warming climate means Ohio winters aren't as cold as they were just a few decades ago, according to National Oceanic and Atmospheric Administration data.

10 Oct 2025

Integrative Genomic Approaches Reveal Mechanisms of Garlic Storability

Garlic (Allium sativum L.) is one of the world's most widely consumed spices and health supplements, with China producing 80% of the international supply.

22 Sep 2025

Pre-Wired T Cells Offer a New Path for Cancer Vaccines

A team of immunologists at the University of Massachusetts Amherst has turned what we know about T-cells, one of the most important parts of the body's immune system, on its head, opening the door to next-generation cancer vaccines.

13 Sep 2025

Ancient Plant Protein Unlocks New Strategy for Engineering Disease-Resistant Crops

Researchers led by Ken Shirasu at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have identified an ancient protein that has the potential to help defend plants against tens of thousands of different bacteria and other pathogens.

5 Sep 2025

New Water-Based Method Extracts High-Purity Lignin

The Nanoscience Center at the University of Jyväskylä discovered that lignin, a polyphenol vital for plant structure, has an antimicrobial effect against viruses and bacteria.

13 Aug 2025

Mapping T Cell Targets to Fight Coronaviruses and Beyond

Most vaccines are designed to provide immunity against just one pathogen. Vaccines for chicken pox (caused by varicella-zoster virus) were only developed to fight that one disease, for example.

8 Aug 2025

New Research Reveals Link Between Copper Antimicrobials and Antibiotic Resistance

Copper has emerged as a key ally in the fight against antibiotic-resistant bacteria. Copper sulfate solutions, for example, have been used since the 1700s to combat fungal infections in vineyards, orchards, and a variety of other agricultural contexts.