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Genomic Database Analysis Identifies New Target for Triple-Negative Breast Tumors

Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

13 Aug 2026

New Study Reveals How Genetic Mutations Hijack the Parkinson's LRRK2 Switch

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

11 Aug 2026

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

Powdery mildew is among the most widespread crop diseases, affecting cereals, grapes, cucurbits, tomatoes, fruit crops, and ornamentals in fields and greenhouses.

5 Aug 2026

AI-Assisted Paper Test Measures Three Cardiac Biomarkers in 23 Minutes

Researchers developed an AI-assisted dual-mode paper assay that measures cTnI, CK-MB, and NT-proBNP from 50 µL of serum in 23 minutes. In single-site analytical validation, neural networks quantified the three biomarkers across distinct concentration ranges, supporting further development for multiplexed cardiac testing at the point of care.

27 Jul 2026

Research Maps Structural Mechanism Linking Amino Acid Availability to Cancer Growth

Cells carry their own growth switches. When enough nutrients-amino acids in particular-are available, cells flip this switch on and begin to grow. Researchers at KAIST and Yonsei University have now uncovered the molecular mechanism by which amino acid signals activate this cellular growth switch.

27 Jul 2026

Lipid Accumulation in Senescent Brain Cells Drives Aging and Alzheimer’s Disease

A new research paper was published in Volume 18 of Aging on July 1, 2026, titled "Senescent cells accumulate lipid droplets."

17 Jul 2026

Short Peptide Molecular Tool Targets Key Diagnostic Disease-Related Proteins

Proteins regulate a wide range of biological processes inside and outside cells by binding to specific molecular partners.

16 Jul 2026

Breakthrough Imaging Method Maps Whole Cell Signals

Cells are crowded, dynamic places where thousands of molecules interact in tight quarters. Until now, scientists lacked a reliable way to see many of these molecular interactions as they happen.

15 Jul 2026

Cancer Cells Hijack Macrophage Metabolism to Create an Immunosuppressive Tumor Microenvironment

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment. However, instead of attacking cancer cells, they are typically co-opted to support tumor growth, metastasis, and therapeutic resistance.

2 Jul 2026

Researchers Identify Crucial Cell Death in Down Syndrome

Researchers at the Alzheimer's Center at Temple have identified evidence of a new form of cell death known as necroptosis in the brains of individuals with Down Syndrome, with the corresponding biomarkers providing new clues to potential treatment also for Alzheimer's and other neurodegenerative diseases.

1 Jul 2026

Mayo Clinic Scientists Discover Molecular Structures of Key Protein

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.

29 Jun 2026

Single Nucleus RNA Sequencing Decodes Tomato Plant Early Stage Development

Seedling emergence is one of the most vulnerable stages in plant life. In darkness, seedlings undergo skotomorphogenesis, forming elongated hypocotyls and curved apical hooks that protect the shoot tip as it pushes through soil.

29 Jun 2026

New Karyoptosis Mechanism Linked to Alzheimer's and Frontotemporal Dementia

Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer's disease and frontotemporal dementia (FTD).

26 Jun 2026

Researchers Outline Dynamic Protein Control Systems for Better Clinical Decisions

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

10 Jun 2026

Cell Phase Separation Creates Droplets That Optimize and Activate Kinase Signaling

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a phenomenon known as phase separation.

2 Jun 2026

Study Connects Lysosomal Lipid Movement Directly to Cellular Growth Signaling

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth beyond the capabilities of normal cells.

25 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

New Study Reveals Mechanism Behind Early Plant Cell Wall Development

Cell walls are a crucial structure of plant life, protecting cells from damage, giving plants shape, and containing energy-rich nutrients. And yet the process of how the walls begin to form remains mysterious.

5 May 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026