Cell Biology

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Novel technique precisely corrects DNA errors in cultured patient cells

Scientists recently created a technique to accurately and quickly correct genetic alterations in the cultivated patient cells.

2 Dec 2021

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Researchers at Queen’s University boarded a modified Falcon 20 aircraft at Ottawa airport on May 22nd, 2019 as part of a scheduled “vomit comet” flight. In this mode of flight, the plane repeatedly climbs in a steep parabola to 8 km, alternating with a freefall descent.

2 Dec 2021

Cytomegalovirus accelerates the decline of the immune system regardless of age

Scientists from the University of Córdoba have been investigating the changes that occur in the T lymphocytes of the immune system with increasing age.

2 Dec 2021

Researchers successfully generated Leydig cells from human iPS cells

Scientists recently succeeded in creating Leydig cells from human induced pluripotent stem (iPS) cells.

2 Dec 2021

Study finds amphipathic peptide that safely opens endosomal membrane

The cell plasma membrane and the derived endosomal membranes are both greasy barriers that prevent the inflow of water-soluble macromolecules like nucleic acids and proteins into cells.

2 Dec 2021

New study shows how neuroblastoma cells deal with rapid division

The cells of a certain tumor type, called neuroblastoma, divide very rapidly. This rapid division can have potentially fatal consequences for them. A new study shows how neuroblastoma cells deal with this dilemma.

1 Dec 2021

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

1 Dec 2021

Researchers show that tumor cells contribute differently to the formation of metastases

A type of cell transformation known as EMT enables cancer cells to break away from the tumor and form metastases elsewhere.

30 Nov 2021

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

Anti-idiotype antibodies may explain the long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. Researchers are working to find effective vaccines and therapies, as well as understand the long-term effects of the infection.

From The University of California, Davis 26 Nov 2021

Novel information leads to identification of new protein communities

If cells are assumed to be “countries”, the proteins will be the citizens structured into inter-connected villages and towns.

25 Nov 2021

Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

A novel therapeutic approach inhibits the growth of metastatic tumors in mice by coercing cancer cells into a dormant state—where they cannot proliferate.

25 Nov 2021

Study develops robust imaging technique to measure in situ oxygen concentration

The advancements in technology might come up with techniques that measure biological parameters in real-time in living organisms, which can help monitor tissue homeostasis, on the go. A significant component of such homeostasis is tissue oxygen concentration.

25 Nov 2021

Study analyzes connections between COVID-19 severity and gene expression

Recent research reveals how genetic variations associated with severe cases of COVID-19 impact the immune cells.

25 Nov 2021

Study identifies key proteins that damage skin cells in psoriasis

Psoriasis is an autoimmune disease that is characterized by patches of red, inflamed skin and painful, scaly rashes.

25 Nov 2021

Viral RNA undergoes conformational changes to hijack host cells, says study

Scientists from the University of Colorado Anschutz Medical Campus recently identified how an RNA molecule from a virus develops a complex, three-dimensional structure, and is capable of changing its shape to hijack host proteins.

25 Nov 2021

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

Researchers develop a new way of simulating cell mechanics

Researchers from The University of Texas at Arlington are working to create a simulation technique that better predicts how stem cells develop into specific cells, such as bone or skin.

25 Nov 2021

UD biochemist explores how mRNA eraser enzymes work in our cells

University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how science can pave the way for possible solutions to this problem.

25 Nov 2021

Study shows why disruption of the body clock leads to inflammatory diseases

New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans.

25 Nov 2021