Cell Biology

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New Solvatochromic Dye Could Revolutionize Real-Time Lipid Order Imaging

A new solvatochromic probe could help shed light on the relationship between lipid membrane fluidity and various cellular functions, report scientists at Tokyo Institute of Technology and Kyushu University.

14 Mar 2024

Research Reveals the Impact of Activated Protein C on Alzheimer's Disease Pathology

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 4, entitled, "Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C."

14 Mar 2024

Dual-Target CAR T Cell Therapy Shows Promise Against Recurrent Glioblastoma

Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024

Study Identifies Protein Key to Preserving Neuronal Identity

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

13 Mar 2024

NIH Researchers Map Vulnerable Sites on Epstein-Barr Virus gp42 Protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

13 Mar 2024

Small Genetic Element Identified as Key to Potato Industry's Production Problem

Researchers have discovered a game changer for the potato industry.

12 Mar 2024

Biological Glue Provides Clues About Cardiovascular Diseases

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

12 Mar 2024

Electron Microscope Unlocks Secrets of the Commander Complex

Receptor molecules on the cell surface are essential for cellular communication. Periodically, these receptors must be absorbed and sorted for them to be broken down or recycled.

12 Mar 2024

Study Reveals STAP-1 Protein's Role in Immune Disorders

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

12 Mar 2024

Reducing Iron May Reverse Stem Cell Aging

It is fascinating to learn how researchers at the Albert Einstein College of Medicine and the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have discovered a way to prevent or even reverse the function of hematopoietic (blood-forming) stem cells (HSCs) as they age.

11 Mar 2024

Breakthrough Study Reveals Key Mechanism in Passing Epigenetic Information During Cell Division

A research team led by Professor Yuanliang ZHAI at the School of Biological Sciences, The University of Hong Kong collaborating with Professor Ning GAO and Professor Qing LI from Peking University, as well as Professor Bik-Kwoon TYE from Cornell University, has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division.

11 Mar 2024

Zebrafish Circadian Clock Unaffected by Lack of Functional Eyes

Functional eyes are not required for a working circadian clock in zebrafish, as a research team including CNRS scientists has now shown.

11 Mar 2024

Blood-Based Markers Unveil Secrets of Biological Aging

University of Pittsburgh researchers have uncovered blood-based markers linked with healthy and rapid aging, allowing them to predict a person's biological age -; how fast a person's cells and organs age regardless of their birthdate.

11 Mar 2024

uLIPSTIC Tool: Tracking Cell-to-Cell Interactions

Gaining an understanding of how various cell types cooperate to form tissues, organs, and organ systems is one of the main objectives of basic biology.

8 Mar 2024

Unraveling the Complexities of Sugar Sensing in Insects

Insects have numerous receptors on their tongues, each of which can detect a different kind of sugar, unlike humans who have a single receptor on their tongues that can detect all kinds of sweets, including artificial sweeteners like aspartame.

7 Mar 2024

The Secrets of Toxic Algal Blooms: A Deep Dive into Prorocentrum cordatum's Cell Biology

Professor Dr Ralf Rabus of the University of Oldenburg has carried out the first comprehensive analyses of the peculiar cell biology of Prorocentrum cordatum, a globally distributed species of the dinoflagellates group.

6 Mar 2024

New Therapeutic Devices for Diseases with ‘Internet of Life’

Although an electronic gadget and E. coli bacteria might not seem to have much in common, University of Maryland researchers recently connected them to create the first closed-loop system capable of communication across the technological and biological divide.

6 Mar 2024

CSHL Researchers Unravel Why Some Splicing-Based Drugs Tend to Work Better Than Others

Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a process called RNA splicing.

6 Mar 2024

Constructing a Structured Illumination Microscopy Add-On

EPFL scientists have recently released a comprehensive manual detailing the construction of an add-on that can transform a regular optical microscope into a cutting-edge tool capable of generating high-resolution, three-dimensional images of cells, organoids, and embryos.

5 Mar 2024