Cell Biology

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Preventing Immunological Rejection Following Transplantation

According to researchers, genetically modified stem cells may also open the door to novel regenerative medicine therapies for conditions including Type 1 diabetes.

12 Jan 2024

Human Conjunctiva Model Developed For First Time

The Hubrecht Institute's Organoid group created the first organoid model of the human conjunctiva. The function of these organoids is mimicked by the human conjunctiva, a tissue involved in the formation of tears.

12 Jan 2024

Unexpected Situations Trigger Chandelier Cell Activity

According to a recent study from the Netherlands Institute for Neuroscience, certain brain cells, known as chandelier cells, become active in unexpected circumstances.

11 Jan 2024

Bacterial "Freight Elevator" Transports Camouflage Molecule for Immune Evasion

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane.

9 Jan 2024

Researchers Decode Immune System's Role in Epigenetic Clocks

When questioned, "What is your age?" The majority of people gauge by counting their birthdays.

9 Jan 2024

AI Program Reveals Cellular Neighborhoods in Cancer Microenvironments

A novel AI-powered program has been developed by researchers at Children's Hospital of Philadelphia (CHOP) to assist in comprehending how various cells arrange themselves into certain tissues and communicate with one another.

9 Jan 2024

Novel Amino Acid Nanoparticles Offer Hope for Fighting Multi-Drug Resistant Cancers

Amino acids, such as tyrosine and tryptophan, are the fundamental building blocks that make up proteins.

9 Jan 2024

Brain's Internal Compass Found to Hold Key to Episodic Memory Formation

Researchers at the University of Tübingen have uncovered new roles for head-direction cells, which may have an impact on the development of episodic memory.

8 Jan 2024

Japanese Scientists Revolutionize Regenerative Lung Medicine

Globally, chronic obstructive pulmonary disease, or COPD, is the third most common cause of mortality. It is characterized by permanent and irreversible lung damage, for which lung transplantation is the only effective treatment. Unfortunately, it is hard to find good lung donors.

8 Jan 2024

Novel Peptides from South American Bushmaster and Pit Viper

The venom of the South American bushmaster, a resident of tropical rainforests, and the pit viper Cotiara, which lives in southern Brazil, both contain fragments of hemorrhagic toxins that may be used to treat high blood pressure.

8 Jan 2024

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

A new study published in Nature Cell Biology by Mark Alkema, PhD, professor of neurobiology, establishes an important molecular link between specific B12-producing bacteria in the gut of the roundworm C. elegans and the production of acetylcholine, a neurotransmitter important to memory and cognitive function.

5 Jan 2024

Research Reveals Unforeseen Functions for Autophagy Genes in Neuronal Health and Aging

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions

5 Jan 2024

Scientists Develop Tiny Human Cerebellums to Decipher Disease and Design Therapies

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

5 Jan 2024

A Pair of Force-Activated Gene Regulating Proteins Guide Fetal Bone Development

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

5 Jan 2024

Unraveling the Mysteries of COPII-Mediated Protein Transport

Similar to postal workers who deliver packages in inclement weather, such as snow, rain, or heat waves, a vital set of proteins found in mammals enables cells to operate normally, even in less-than-ideal circumstances.

4 Jan 2024

Zipping Up Chromosomes: The Synaptonemal Complex Revealed

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability.

4 Jan 2024