Genomics

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Identification of Unique Proteins That Might be Body Weight Regulators

Genetic factors may account for up to 50% of the diversity in body mass index, or BMI, in the population.

5 Apr 2023

SoyOmics: An Innovative Framework of Multi-omics Database for Soybean

A major source of plant oil and protein for humans is the soybean (Glycine max (L.) Merr.), a crop cultivated all over the globe. The main objective for geneticists and breeders is to increase soybean production and quality.

5 Apr 2023

Male Beetles Neglect Maintenance of Gametes When Competing for Mating Opportunities

Male beetles face a trade-off between competing with other males for mating opportunities and repairing damage to their sperm DNA, according to a study publishing April 4th in the open access journal PLOS Biology by Mareike Koppik from Uppsala University, Sweden, and colleagues.

5 Apr 2023

Novel Genes Could Serve as Predictive Biomarkers for PARP Inhibitor Response in Prostate Cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

5 Apr 2023

Endothelial Deletion of Wt1 Gene During Coronary Vessel Formation Affects Embryonic Heart Development

How is the mammals' heart formed? What role do endothelial cells play? Do the same pathways and genes involved in the formation of the embryonic heart also play a role in repair processes?

4 Apr 2023

Study Offers New Insight into Genetic Factors Behind Premature Delivery and Gestational Duration

New knowledge of the genetic factors behind premature delivery and gestational duration has now emerged.

4 Apr 2023

Cold Temperature Increases Human Life Expectancy

Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.

4 Apr 2023

Jumping Genes in Various Cancers may be Used to Direct Novel Immunotherapies to Tumors

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

4 Apr 2023

New Resource Provides a Better Annotation of the Genome and Understanding of Variant Impact

Each person has about 4 million sequence differences in their genome relative to the reference human genome.

4 Apr 2023

KAI2-Ligand Signaling Pathway Responsible for Regulating Vegetative Reproduction in Liverwort Plants

Asexual, or vegetative, reproduction in plants is controlled by environmental conditions, but the molecular signaling pathways that control this process are poorly understood.

3 Apr 2023

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

3 Apr 2023

Two types of immune cells interact to give natural protection from tuberculosis

A new study has uncovered the role of B and T cells in controlling tuberculosis (TB) infections.

3 Apr 2023

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

31 Mar 2023

Personal genome sequencing and personalized medicine

Genetic mutations have given life on Earth a stunning variety of various sizes, colors, and shapes. Some changes are beneficial, while others are dangerous or ineffective. There are about 4.5 million genetic variants per individual.

31 Mar 2023

Gene variants that improve nitrogen utilization identified

Nitrogen as a fertilizer can boost yields. Too much nitrogen, on the other hand, can have negative consequences such as high energy consumption in fertilizer manufacturing.

31 Mar 2023

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

31 Mar 2023

BGI Genomics and Zentya collaborate to launch COLOTECT in Slovakia

BGI Genomics is pleased to announce the launch of COLOTECTTM 1.0 in Slovakia, in collaboration with its local partner, Zentya. Zentya is a Slovak-based healthcare solution provider that is passionate about providing patients with the latest technology in the field of genetic screening, aiming to help identify and facilitate timely treatments of genetic diseases.

31 Mar 2023

Rare genetic variants identified that point to MAC as a therapeutic target for age-related macular degeneration

A new study conducted at the National Eye Institute (NEI) has identified incredibly rare genetic variants that might uncover the mechanisms underlying the development of AMD.

31 Mar 2023

Research shows how the fruit fly gut builds a cozy niche to selectively promote colonization

The digestive tract of fruit flies remodels itself to accommodate beneficial microbiome species and maintain long-term stability of the gut environment, according to new research led by Carnegie's William Ludington and Allan Spradling.

30 Mar 2023

Genomics

Identification of Unique Proteins That Might be Body Weight Regulators

SoyOmics: An Innovative Framework of Multi-omics Database for Soybean

Male Beetles Neglect Maintenance of Gametes When Competing for Mating Opportunities

Novel Genes Could Serve as Predictive Biomarkers for PARP Inhibitor Response in Prostate Cancer

Endothelial Deletion of Wt1 Gene During Coronary Vessel Formation Affects Embryonic Heart Development

Study Offers New Insight into Genetic Factors Behind Premature Delivery and Gestational Duration

Cold Temperature Increases Human Life Expectancy

Jumping Genes in Various Cancers may be Used to Direct Novel Immunotherapies to Tumors

New Resource Provides a Better Annotation of the Genome and Understanding of Variant Impact

KAI2-Ligand Signaling Pathway Responsible for Regulating Vegetative Reproduction in Liverwort Plants

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

Two types of immune cells interact to give natural protection from tuberculosis

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

Personal genome sequencing and personalized medicine

Gene variants that improve nitrogen utilization identified

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

BGI Genomics and Zentya collaborate to launch COLOTECT in Slovakia

Rare genetic variants identified that point to MAC as a therapeutic target for age-related macular degeneration

Research shows how the fruit fly gut builds a cozy niche to selectively promote colonization

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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