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Improving drug targets for asthma and rheumatoid arthritis

Researchers have found that immune T cells exhibit a range of responsiveness. This finding could offer insights into how the immune system of humans responds to infections and cancer, and what goes wrong in immune diseases.

16 Apr 2020

New method images proteins in 3D with nanoscale resolution

A research team, which also included scientists from the National Synchrotron Light Source II (NSLS-II), has reported a novel method for imaging proteins in three dimensions (3D) with nanoscale resolution.

16 Apr 2020

New method can improve access to sophisticated microscopy data

Researchers from the University of Michigan Life Sciences Institute (LSI) have created a novel data-processing method that offers a simpler yet faster way to data produced by cryo-electron microscopy (Cryo-EM) instruments, thus making it possible to adopt this robust method at a wider scale.

16 Apr 2020

New algorithm predicts the evolution of genetic mutations in species

David McCandlish and Juannan Zhou, both quantitative biologists at the Cold Spring Harbor Laboratory, have designed a new algorithm that has predictive power, providing researchers the ability to observe the way particular genetic mutations combine to make crucial proteins change over the duration of a species’ evolution.

16 Apr 2020

Novel high-speed microscope successfully records neural activities

Our brain contains tens of billions of nerve cells (neurons) which constantly communicate with each other by sending chemical and electrical flashes, each lasting a short one millisecond (0.001 sec). In every millisecond, these billions of swift-flying flashes altogether traveling in a giant star-map in the brain that lights up a tortuous glittering pattern.

15 Apr 2020

Genetic architecture of life span is context dependent, study finds

Scientists believe about 25 percent of the differences in human life span is determined by genetics -- with the rest determined by environmental and lifestyle factors. But they don't yet know all the genes that contribute to a long life.

15 Apr 2020

Molecular causes of brain asymmetry revealed

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are "right-brained" while others are "left-brained."

15 Apr 2020

Scientists determine first 3D structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

15 Apr 2020

Research provides new insights into building blocks of gum disease

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

15 Apr 2020

Study offers insight into exchange of drug resistance genes among bacteria

Researchers have been able to identify and track the exchange of genes among bacteria that allow them to become resistant to drugs, according to a new study published today in eLife.

15 Apr 2020

How human cells recognize undesirable guests

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

DeNovix launches new RNA quantification assay

DeNovix Inc., a developer and manufacturer of instrumentation and assays for the life sciences, introduces a new RNA fluorescence quantification assay. The assay is suitable for multiple platforms including stand-alone fluorometers, plate readers or any DeNovix fluorescence based instrument.

From DeNovix Inc. 15 Apr 2020

Plant genes control microbiome diversity inside leaves to stay healthy

In a new study, published in the journal Nature, Michigan State University scientists show how plant genes select which microbes get to live inside their leaves in order to stay healthy.

14 Apr 2020

Clock protein moves in sync with temperature to coordinate rhythms in shoots, roots

Five years ago, researchers from the Centre for Research in Agricultural Genomics led by the CSIC Research Professor Paloma Mas made the breakthrough discovery that the circadian clocks in the growing tip of the plant shoot function in a similar way to the clocks in the mammalian brain, which in both cases are able to synchronize the daily rhythms of the cells in distal organs.

14 Apr 2020