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New Insights into How Early Life Experiences Influence Genetic Expression and Brain Health

In a comprehensive Genomic Press Interview, renowned neuroscientist Dr. Michael Meaney reveals pivotal discoveries about the intricate relationship between genes and environment in shaping brain health.

2 Jan 2025

New Sequencing Method Unveils Adaptive States and Host-Phage Interactions in the Gut

The human gut microbiome is complex and diverse, with significant implications for health and disease. The study develops smRandom-seq2, a droplet-based method that overcomes the limitations of existing techniques by capturing RNA from a wide variety of species.

2 Jan 2025

Ancient DNA Analysis Unveils Migration Patterns in Early Europe

Waves of human migration across Europe during the first millennium AD have been revealed using a more precise method of analyzing ancestry with ancient DNA, in research led by the Francis Crick Institute.

2 Jan 2025

Genetic Sequencing Breakthrough Reveals Rapid Spread of New Pathogens

Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.

2 Jan 2025

Study Reveals Mechanism Behind Retrotransposon Insertion in Centromeres

A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around" chromosomes and are known drivers of evolution, preferentially insert in the centromere.

2 Jan 2025

Uncovering the Cellular Mechanisms of Brain Aging

Not all brain cell types age in the same way, according to new brain mapping research supported by the National Institutes of Health (NIH).

2 Jan 2025

New Model for Studying Ebola Virus Pathogenesis

Ebola is a fatal hemorrhagic disease caused by a virus that is found in parts of East-Central and West Africa. Most individuals are aware that the major mode of person-to-person transmission is through contact with an infected person’s bodily fluids.

2 Jan 2025

Bacterial Protein Enables 2D Culture of Organoids

The Organoid group’s researchers devised a novel method for growing organoids. Organoids are miniature organs that are created in a lab and resemble the original organ.

2 Jan 2025

Bumetanide Treatment Alters Early and Late Social Behaviors in Fragile X Mice

In a comprehensive Genomic Press Interview, researchers from the University of Texas Health Science Center at San Antonio and Hirosaki University have uncovered critical new insights into the developmental trajectory of social behaviors in fragile X syndrome, the leading genetic cause of autism spectrum disorder.

30 Dec 2024

Research Reveals Regulatory Role of Glucose-6-Phosphate Dehydrogenase in Mitophagy

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway.

30 Dec 2024

New Studies Investigate Microbial Interactions and Nutrient Exchange in Soils

Communities of microbes (microbiomes), particularly in soils, can be startlingly diverse, with as many as 10,000 species in just a cup of material.

27 Dec 2024

New HG-TCs Strategy Enables Efficient Analysis of Glycosylation in Cells

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.

27 Dec 2024

Scientists Develop Non-Destructive Method to Study Fish Teeth

Can we examine the teeth of living fish and other vertebrates in detail, repeatedly over time, without harming them?

27 Dec 2024

AI-Designed Nanocages Mimic Intricate Structures of Viruses

Professor Sangmin Lee from POSTECH's Department of Chemical Engineering, in collaboration with 2024 Nobel Chemistry Laureate Professor David Baker from the University of Washington, has developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence (AI).

26 Dec 2024

Stress Pathway in Microglia Found to Contribute to Alzheimer's Neurodegeneration

Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD).

26 Dec 2024

New Platform Simplifies Protein-Protein Interaction Measurements

A team led by researchers at the University of Toronto has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy.

26 Dec 2024

New Study Reveals DNA’s Role in Stabilizing Cellular Structures

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life: DNA and the element magnesium.

26 Dec 2024

Fruit Flies Evolve New Defense Through Gene Transfer

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition.

26 Dec 2024

New Gene Editing Tool Targets Alzheimer's by Skipping Disease-Causing Gene Segments

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

24 Dec 2024

Plant Research Reveals Unexpected Function for Key Cellular Protein

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's genetic code expresses itself. The fundamental breakthrough was discovered in apple cells but is relevant to all living organisms made of nucleus-containing cells, including humans.

24 Dec 2024