Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Scientists Engineer E. Coli To Produce Plastic-Building Chemical

This study reveals a novel pathway in E. coli for synthesizing 2,5-pyridinedicarboxylate from glucose, offering a sustainable alternative to fossil fuels.

10 Sep 2025

How Defined Microbes Decide Chocolate Flavor

This study links microbial activity and fermentation conditions to cocoa flavor profiles, advancing techniques for producing premium chocolate consistently.

27 Aug 2025

Breakthrough Technique Enables Large-Scale Study of Polar and Ionic Metabolites

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

The study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.

6 Aug 2025

Fidelio Capital Partners with Alphalyse to Accelerate the Global Roll-Out of LC-MS Host Cell Protein Analytics

Alphalyse, a fast-growing Danish specialist contract research organization (CRO) that has developed GMP‑validated liquid‑chromatography mass‑spectrometry (LC‑MS) assays for host‑cell‑protein (HCP) impurity testing in biologic drugs, today announces that Fidelio Capital has acquired a majority stake in the company.

From Alphalyse A/S 2 Jul 2025

Collagen and Chitin Amendments Support Soil Microbes to Control Nematode Infections

Collagen and chitin shift soil microbial communities and reduce root-knot nematode infections in tomato plants while improving plant growth and chlorophyll content.

23 Jun 2025

Natural Deep Eutectic Solvents Enhance Yield and Antibacterial Activity of Zanthoxylum bungeanum

NADES treatments significantly boost essential oil yield and antibacterial activity in Zanthoxylum bungeanum, offering a natural solution to food contamination.

23 May 2025

Addressing Protein Leakage in Cells to Improve the Accuracy of Single-Cell Proteomic Data

A new study in Nature Communications presents a solution to protein leakage in single-cell proteomics, improving data quality by identifying and excluding permeabilized cells using a machine learning classifier.

19 May 2025

Sustainable Recycling: Turning Expired Pet Food into Biodiesel and Livestock Feed with Black Soldier Fly Larvae

A new study explores the use of black soldier fly larvae to convert expired pet food into biodiesel and animal feed. This sustainable biorefinery approach offers a low-emission, efficient solution for organic waste management and circular meat production.

14 May 2025

Depleting TM6SF2 in the Gut Worsens Liver Fat Buildup, Study Finds

A new study finds that gut-specific TM6SF2 depletion exacerbates liver fat accumulation and dysbiosis in mice on high-fat diets, highlighting its importance in gut-liver metabolic regulation.

12 May 2025

Restoring Alpha-Synuclein to Support Synaptic Function and Neurotransmission

A new study reveals how restoring α-synuclein levels can help preserve synaptic vesicle composition and function, offering therapeutic insights for Parkinson’s and other neurodegenerative diseases.

7 May 2025

Dangerous Synthetic Opioids and Animal Sedatives Not Approved for Human Use Have Been Found in Australia's Wastewater

University of South Australia scientists have developed a highly sensitive method to detect illegal opioids and a veterinary sedative in Australia’s wastewater system, providing a vital early warning tool to public health authorities.

28 Apr 2025

How P. syringae Outsmarts Amoeba with Chemical Surveillance and Strikes

Pseudomonas syringae's chemical sensing system allows it to kill amoeba predators, showcasing its evolutionary strategies for survival and plant infection.

14 Apr 2025

Flies Get Drunk on Purpose—But Not for the Reasons You Think

Drosophila flies show a strong attraction to ethanol and methanol, driven by evolutionary benefits in mating success rather than psychological responses.

11 Apr 2025

Unraveling the Interaction Between Mitochondrial Proteins HAX1 and CLPB

A recent study published in Magnetic Resonance Letters has revealed for the first time the interaction mechanism between the mitochondrial proteins HAX1 and CLPB, filling the research gap between these two key proteins in the field of structural dynamics and functional association.

10 Apr 2025