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Study Shows How Genetic Switches Help 3D Printed Bone Grow Blood Vessels

An interdisciplinary team of engineers and chemists at Penn State has laid the groundwork to 3D print spheroids - tiny clusters of living cells - capable of regenerating bone tissue in response to severe trauma or infections.

19 Aug 2026

Researchers Develop Invisible Cell Armor for Safer Diabetes Treatment

Innovative hydrogel cloaking of islets could revolutionize diabetes therapy, allowing for effective cell transplantation without compromising immune function.

18 Aug 2026

Localized Biochemical Halos Shield Pancreatic Beta Cells From Rejection

A protein known as interleukin 10 (IL-10) is the lynchpin of a new method to protect transplanted cells from host immune system aggression.

6 Aug 2026

Microneedle Patches Turn Skin Into a Window for Immune Bioanalysis

Researchers combined local restimulation of skin-resident memory T cells with hydrogel-coated microneedle patches to recruit and sample rare immune cells. In mouse models, the approach recovered more antigen-specific T cells than a blood sample or punch biopsy, while studies in humans supported short-term tolerability and proof-of-concept cell sampling.

28 Jul 2026

Dying Bacterial Communities Eject Cells Just Like Sci-Fi Escape Pods

Popular science fiction is no stranger to escape pod scenarios, typically featuring characters who narrowly avoid their demise by jettisoning from a spaceship - think R2-D2 and C-3PO shooting away from a rebel spaceship in the opening of Star Wars: A New Hope.

7 Jul 2026

New 3D-Printed Trays Help Produce Functioning Human Gut Organoids Twice as Fast

Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children's, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods-and these organoids grow their own nerve cells.

23 May 2026

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Researchers developed a 3D liver model that functions for a month, replicating inflammation and fibrosis, crucial for studying liver diseases and therapies.

19 May 2026

Visualizing Immune Synapses in Three Dimensions Using Cryo-Expansion Microscopy

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells.

30 Apr 2026

Implantable Cell Factory Device Delivers Sustained Biologic Drug Production

Implanting living cells as long-term drug producers could transform treatment for numerous diseases, but it is difficult to house the tiny workers in quantities high enough to ensure dosage needs are met while also keeping the cells alive and thriving.

28 Mar 2026

Research Shows Successful Recovery of Antigen-Specific T Cells in Mouse Models

Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body's immune responses painlessly from the skin. The device detects inflammatory signals within minutes and collects specialized immune cells within hours without the need for blood draws or surgical biopsies.

3 Mar 2026

Novel Hydrogel Stops Infection and Speeds Wound Recovery

A novel gel might help combat resistant bacteria in wounds and around implant sites while also promoting recovery. The hydrogel, which is inspired by natural immune defenses, has generated extremely encouraging outcomes in animal models.

4 Feb 2026

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

This review highlights the potential of natural polysaccharide microneedles in cancer immunotherapy, focusing on localized treatment and immune activation.

7 Jan 2026

Smart Hydrogel Senses Infected Wounds and Delivers the Right Treatment

The novel hydrogel adapts to wound environments, offering precise antibacterial and regenerative support, addressing the challenges of infected wounds.

18 Dec 2025

New Tunable Device Enables Precise Size-Based Sorting of Cancer Cells

Poly(N-isopropylacrylamide) (PNIPAM) hydrogel undergoes significant but precise changes in size between 20 and 40 °C, making it an excellent candidate for use in variable-size deterministic lateral displacement (DLD) array devices.

8 Dec 2025

Mapping the Molecular Choreography of Nuclear Pore Transport

Nuclear pore complexes (NPCs) are tiny but sophisticated gatekeepers that control the flow of materials between a cell's nucleus and its cytoplasm by quickly selecting which molecules to transport across the nuclear membrane.

22 Oct 2025

Injectable Hydrogels Use Milk-Derived Vesicles to Promote Tissue Regeneration

Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.

29 Jul 2025

The Future of Chicken? Scientists Grow Whole Cuts in a Bioreactor

This research introduces a hollow fiber bioreactor for cultured chicken meat, optimizing tissue engineering with enhanced perfusion and structural integrity.

25 Apr 2025

Likarda Paper Highlights Hydrogel Encapsulation with CSS Can Overcome Major Obstacle of Liver Cell Therapies

Likarda, a leading biotech company specializing in the development of enabling technologies for the delivery of both cell therapies and large molecule biologics, announced a new peer-reviewed publication that demonstrates a promising improvement in the effort to develop liver cell-based therapies for patients with chronic liver disease.

23 Apr 2025

Researchers Develop Cellulose-Based 3D Scaffolds That Mimic Natural Tissue Architecture

This research outlines a protocol for nano-fibrillated cellulose scaffolds, crucial for tissue engineering, emphasizing mechanical stability and cell viability.

9 Apr 2025

Allegro’s Injectable Osteoarthritis Treatment Generates Positive Safety Results in Preclinical Studies

Allegro NV, a biomedical company developing transformative nanotechnology-based treatments for degenerative joint disease, has found that hydrocelin (ALG-001), its injectable microparticle hydrogel, showed no signs of toxicity in two preclinical studies conducted for periods of 4 and 13 weeks respectively.

25 Mar 2025