Liquid Chromatography News and Research

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Organic Flour May Contain Fewer Pesticides, but What About Other Contaminants?

Researchers testing 96 wheat flours sold in France found pesticide residues or a pesticide synergist in 26% of samples and at least one mycotoxin in 76%, with seven recorded exceedances of European reference thresholds. Conventional flours were more likely to contain pesticide residues, while organic flours had higher concentrations of several mycotoxins and trace metals, raising questions about food safety across different farming and processing systems.

22 Oct 2026

Functional Genomics Platform Connects Candidate Genes to Pest Defense Phenotypes

Cowpea (Vigna unguiculata) supplies dietary protein, livestock feed, and income in tropical and subtropical regions, while its nitrogen-fixing ability adds agricultural value. Genome sequencing has provided researchers with numerous candidate genes, and genetic transformation has enabled studies of traits such as drought and heat tolerance.

20 Oct 2026

Mobile Genetic Elements and Reservoir Type Drive Resistance-Gene Abundance in Water Sources

Aquatic environments are recognized as reservoirs and pathways for antimicrobial resistance, receiving antibiotic residues and resistant microorganisms from sewage, livestock farming, and aquaculture. Previous studies have detected resistance genes in drinking water sources and shown that conventional treatment may remove them incompletely.

16 Oct 2026

Targeting Neural Chloride Homeostasis Mitigates Motor Deficits in Dystrophic Mice

DMD is a severe X-linked disorder caused by dystrophin deficiency and is characterized by progressive muscle degeneration and weakness.

14 Oct 2026

Targeting Host Cellular Repair Mechanisms Enhances Tissue Resistance to Infection

Epithelial cells form the body's frontline barriers, helping keep microbes, toxins, and other harmful substances out. Yet these protective cells are constantly exposed to threats, including microbial infections.

6 Oct 2026

Engineered Citrus Enzyme Transforms Upstream Precursors Into Bioactive Flavones

Polymethoxyflavones (PMFs) accumulate mainly in the colored outer peel, or flavedo, of citrus fruit and are associated with anticancer, anti-inflammatory, metabolic-protective, and neuroprotective activities reported in experimental studies.

12 Sep 2026

SMART Researchers Discover First PLP-Dependent Enzyme That Influences Bacterial Protein Production

Researchers from the Singapore-MIT Alliance for Research & Technology’s (SMART) Antimicrobial Resistance (AMR) interdisciplinary research group, alongside collaborators from Massachusetts Institute of Technology (MIT), Nanyang Technological University (NTU Singapore), and institutions in the United States, Poland, and France, have discovered aminovaleramididine synthetase (AvaS), the first identified pyridoxal phosphate (PLP)-dependent enzyme responsible for producing a chemical modification linked to how bacteria respond to metabolic stress.

10 Sep 2026

Open Sesame: Can Plants Acquire Genes from the Species They Parasitize On?

A new study shows how Cuscuta plants acquire and repurpose a functional gene from a host species through horizontal gene transfer, thereby enhancing metabolic diversity.

8 Sep 2026

Study Shows How Arginine Rich Proteins Fool Immune Reactions to Medical Implants

Proteins with exposed arginine can selectively accumulate even on protein-resistant coatings, as reported by researchers from Science Tokyo.

2 Sep 2026

Colorectal Cancer and Nerve Damage: A Hidden Link Uncovered in Mice and Primates

Colorectal tumors trigger inflammatory nerve damage, suggesting cancer itself may be a risk factor for neuropathy in survivors, independent of treatments.

27 Aug 2026

International Team Establishes Standardized Nomenclature For Selenosugar Research

Selenosugars are the major urinary metabolites responsible for the physiological excretion of selenium. Understanding selenium metabolism relies on accurately detecting and identifying selenosugars.

21 Aug 2026

Origami-Inspired Capsule Shows Promise for Multi-Day Dosing and Sustained Drug Release

An innovative origami-inspired capsule designed by MIT offers extended drug release, improving treatment efficacy and reducing preventable healthcare costs.

11 Aug 2026

Researchers Uncover Molecular Defenses in Cold-Resilient Loquat

Loquat (Eriobotrya japonica) is an evergreen fruit tree whose winter growth and flowering make it especially vulnerable to sudden freezes.

10 Aug 2026

Salt Toxicity Impacts Yields and Herbal Quality of Salvia Miltiorrhiza

Salt stress is one of the most destructive environmental threats to crop production, causing osmotic imbalance, ion toxicity, and oxidative damage that stunt growth and reduce yields.

3 Aug 2026

Fermented Tea Seed Oil Improves Hydration and Reduces Redness in Sensitive Skin

A four-week, half-face clinical trial in 25 young Chinese women found that a moisturizer containing 5% fermented tea seed oil improved skin hydration, redness, and measured wrinkle appearance. Treatment was also associated with broader changes in skin lipid profiles and selected microbial taxa, although the study did not establish causality or compare fermented with unfermented tea seed oil.

12 Jul 2026

Winery Waste Becomes Stable Squalane for Greener Cosmetics

Researchers developed an eco-friendly workflow to recover squalene from wine lees using ultrasound-assisted extraction and convert it into more stable squalane using clay-supported palladium catalysts. The upcycled squalane showed improved oxidative stability and enhanced quercetin transport across an artificial membrane, supporting its potential as a sustainable cosmetic excipient.

9 Jul 2026

Evosep and Molecular You Announce Strategic Collaboration to Scale Standardized Multi-Omic Testing Globally

Evosep and Molecular You today announced a strategic collaboration to advance standardized, high-throughput multi-omic testing for personalized biomarker profiling.

From Evosep 3 Jun 2026

Ovarian Cancer Fluid Helps Tumors Evade Cell Death

Ascites in ovarian cancer rewires tumor metabolism, protecting cells from ferroptosis and promoting metastasis, revealing potential therapeutic targets.

27 May 2026

Can Everyday Supplements Lead to Failed Anti-Doping Tests?

Researchers developed a high-throughput LC-MS/MS platform that screened 331 pharmacologically active compounds and quantitatively validated 214 analytes across representative food matrices. Applied to 78 commercial foods and supplements, the framework showed that some products could produce modeled urinary concentrations exceeding WADA reporting thresholds under realistic intake scenarios.

19 May 2026

Next-Generation Mass Spectrometry Reveals How DIA Deepens Proteome Coverage

A multivendor comparison in a neonatal mouse model of bronchopulmonary dysplasia found that DIA, especially on next-generation platforms such as Orbitrap Astral and timsTOF Ultra, greatly expanded peptide and protein detection while preserving broad biological concordance. The deeper coverage improved subcellular and pathway annotation, increased differential protein detection, and reduced estimated sample-size needs, although platform-specific technical differences still complicated direct comparisons.

19 Apr 2026