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Bifidobacterium in Maternal Gut Found to Alter Fetal Brain Growth

Bifidobacterium breve supplementation in pregnant mice alters fetal brain metabolism, highlighting its role in enhancing gestational health and development.

29 Aug 2024

Engineering Cyanobacteria-Yeast Systems for Synthetic Biology

Using evolution as a guiding principle, researchers have successfully engineered bacteria-yeast hybrids to perform photosynthetic carbon assimilation, generate cellular energy and support yeast growth without traditional carbon feedstocks like glucose or glycerol.

27 Aug 2024

Mother's Gut Microbiome Key to Baby's Brain Development

A study in mice has discovered that the presence of Bifidobacterium breve bacteria in the mother's gut during pregnancy promotes healthy brain development in the fetus.

22 Aug 2024

Enzyme Therapy Shows Promise for Parkinson's Disease

A preclinical investigation conducted by Weill Cornell Medicine researchers has shown an unexpectedly important role for an enzyme called PGK1 in the synthesis of chemical energy in brain cells.

22 Aug 2024

Researchers Uncover Role of OpgH in Bacterial Cell Shape

In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's "envelope" or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.

16 Aug 2024

Emerging Treatments and Drug Repositioning for NAFLD and NASH

The current research on drug candidates and molecular targets being clinically tested for the treatment of non-alcoholic steatohepatitis (NASH) and NAFLD.

9 Aug 2024

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

The prevalence of kidney disease has been increasing in Japan, with it now affecting one in eight adults, but developing effective treatment remains a challenge.

24 Jul 2024

Breakthrough Study Reveals How Toxoplasma gondii Alters Host Cell Metabolism

Toxoplasma gondii is a parasite responsible for toxoplasmosis, a lifelong chronic infection prevalent in about 30% of the human population.

12 Jul 2024

UCL Study Uncovers Astrocytes' Role in Brain Energy Boosting Mechanism

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

4 Jul 2024

Metabolic Priming of CAR T Cells for Treatment of Solid Tumors

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently.

3 Jul 2024

Targeting Pseudomonas aeruginosa Cell Wall Stress for Biofilm Control

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics.

2 Jul 2024

DeepEvo: Revolutionizing Protein Engineering with Artificial Intelligence

Engineering proteins for desirable traits has been the holy grail of modern biotechnology.

1 Jul 2024

High-Pressure Processing Revolutionizes Food And Pharmaceutical Industries

How high pressure impacts protein structure, unfolding, refolding, and crystallization.

1 Jul 2024

Mapping Gene Targets of HNF4A and HNF1A in Human Pancreatic Beta Cells and Liver Cells

Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells.

26 Jun 2024

Mitochondria Influence the Ability of Adult Cardiac Cells to Multiply

Whether forcing adult cardiomyocytes to reverse from the oxidative phosphorylation phenotype to the glycolysis phenotype would also restore their mitotic ability.

13 Jun 2024

New Study Reveals Microbial Role in Soil Carbon Emissions

When soil microbes eat plant matter, the digested food follows one of two pathways. Either the microbe uses the food to build its own body, or it respires its meal as carbon dioxide (CO2) into the atmosphere.

12 Jun 2024

Mitochondrial Phosphate Carrier MIR1: A Key Player in Candida albicans Virulence

This study is led by Professor Yan Wang (School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai, China). Her team found that the lack of MIR1 gene, which encodes mitochondrial phosphate carrier, can lead to severe virulence defects in Candida albicans.

23 May 2024