Lyophilized methacrylated Type I collagen in the amount of 100 mg is called PhotoCol®. PhotoCol® offers native-like 3D collagen gels that may be created at varied concentrations and photocrosslinked (needs a photoinitiator) to deliver varying gel stiffness.

PhotoCol® kits comprise purified methacrylated Type I bovine collagen as the core component along with other support reagents present in the kit. This PhotoCol® product just consists of methacrylate collagen. The kits each consist of the first three rows displayed below and come with the chosen photoinitiator.


Image Credit: Advanced BioMatrix

Table 1. Source: Advanced BioMatrix

Item Catalog Number Package Size Storage Temperature
Methacrylated Collagen #5198 100 mg 2-10 °C
20 mM Acetic Acid #5079 50 mL 2-30 °C
Neutralization Solution #5205 10 mL Room Temperature


The methacrylated Type I collagen has been produced from telo-peptide intact bovine collagen where the collagen has been subjected to alteration by reacting with the free amines.

This is mainly the ε-amines groups of the lysine residues as well as the a-amines groups on the N-termini. Almost, >20% of the total lysine residues of the collagen molecule have been methacrylated. The collagen has been withdrawn from the bovine hide and consists of a high monomer content.

Table 2. Source: Advanced BioMatrix

Parameter, Testing, and Method Methacrylated Collagen #5198
Sterilization Method Filtration
Extraction Method Acid - Telocollagen
Form Lyophilized Powder
Degree of Methacrylation ≥ 20%
Package Size 100 mg
Storage Temperature 2-10 °C
Shelf Life Minimum of 6 months from date of receipt
Shelf Life After Reconstitution 2 months
Collagen Purity - Silver Staining ≥ 99%
Kinetic Gel Test (Minutes) ≤ 40
Gel Formation Tube Test (Minutes) ≤ 40
Electrophoretic Pattern - Coomassie Blue Characteristic
Sterility - USP modified No growth
Endotoxin (LAL) ≤ 10.0 EU/mL
Source Bovine Hide
Hydrogel Young's Modulus E (Pa) Characteristic

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