A special solution developed for 2D coatings or 3D hydrogels is TeloCol-6, which is 50 mL of 6 mg/ml, type I bovine telocollagen.

This kit is available with a neutralization solution for simple handling and preparation. Being a higher concentration telocollagen, TeloCol-6 will polymerize rapidly and develop powerful hydrogels compared to atelocollagen.

TeloCol®-6 bovine collagen solution has been acquired from an acid extraction process providing telopeptide-intact collagen. TeloCol® seems to be soluble telocollagen in 0.01 N HCL. The telopeptide regions present at both ends of the collagen chain, N- and C-telopeptide regions, are retained.

Approximately, TeloCol®-6 collagen is 95% Type I collagen with the leftover consisting of Type III collagen. Every product contains a bottle comprising 50 ml of collagen solution joined with a bottle of pre-formulated neutralizing solution for the development of a collagen gel.

This product has been delivered at a concentration of nearly 6 mg/ml. TeloCol®-6 is sterile filtered and offered in easy-to-use packaging for use and storage.

TeloCol®-6 is perfect for coating surfaces, offering preparation of thin layers for culturing cells, or using as a solid gel.


Image Credit: Advanced Biomatrix

Source: Advanced Biomatrix

Parameter, Testing, and Method TeloCol®-6 Type I Collagen #5225
Sterilization Method Filtration
Extraction Method Acid - telocollagen
Form Solution
Package Size 50 mL Kit
Storage Temperature of Collagen 2-10 °C
Storage Temperature of Neutralization Solution Room Temperature
Shelf Life Minimum of 6 months from date of receipt
Collagen Concentration - Biuret 5.8-6.8 mg/mL
Collagen Purity - Silver Staining ≥ 99%
pH 1.9-3.0
Kinetic Gel Test (Minutes) ≤ 40
Gel Formation Tube Test (Minutes) ≤ 40
Fibrillogenesis (Absorbance Units) ≥ 0.35
Electrophoretic Pattern - Coomassie Blue Characteristic
Sterility - USP modified No growth
Endotoxin - LAL ≤ 10.0 EU/mL
Osmolality (mOsmo H2O/kg) ≤ 35
Cell Attachment Assay Pass
Source Bovine Hide
Hydrogel Young's Modulus E (Pa) Characteristic

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