Overview
PhotoDextran® from Advanced Matrix is known to be a 1 gm of lyophilized methacrylated dextran. PhotoDextran® offers 3D hydrogels that could be made at multiple concentrations and photocrosslinked (needs a photoinitiator).
This is done to offer several gel stiffnesses. Also, it could be mixed with other photocrosslinkable ECMs.
Advanced BioMatrix provides PhotoDextran®, a methacrylated dextran for photocrosslinkable hydrogels or integrating inside photocrosslinkable hydrogels (like PhotoCol, PhotoGel, or PhotoHA).
PhotoDextran® offers native-like 3D gels with special attributes: It could be made at several concentrations and photocrosslinked in a range of methods to offer a truly tunable gel stiffness. PhotoDextran® could be ordered by itself (1 gm lyophilized sterile powder), or as a kit that is available with a photoinitiator for photocrosslinking.
Image Credit: Advanced Matrix
Table 1. Source: Advanced Matrix
| Item |
Catalog Number |
Photoinitiator Included |
| PhotoDextran |
#5311 |
N/A |
| PhotoDextran with Irgacure |
#5331 |
Irgacure (365 nm) |
| PhotoDextran with LAP |
#5332 |
LAP (405 nm) |
| PhotoDextran with Ruthenium |
#5333 |
Ruthenium (400-450 nm) |
As soon as it is solubilized, the PhotoDextran® could be stored at 2 to 10 °C for almost one month.
Table 2. Source: Advanced Matrix
| Parameter, Testing, and Method |
Methacrylated Dextran #5311 |
| Sterilization Method |
Filtration |
| Sterility - USP modified |
No growth |
| Form |
Lyophilized Powder |
| Package Size |
1 gram |
| Storage Temperature |
-20 °C |
| Shelf Life |
Minimum of 6 months from date of receipt |
| Shelf Life After Reconstitution |
1 Month |
| Degree of Methacrylation |
45-65% |
| Molecular Weight |
35,000-50,000 Da |
| Endotoxin - IU/g |
<10 |